• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

Amino Acids 40 Profile- any ideas?

Messages
97
Just got the results from my amino acids profile here:

Low- Tyrosine
Low- Glutamine
Low- Isoleucine

High- Taurine
High- Serine
High- Phosphoethanolamine
High- Glutamic Acid
High- 1-Methylhistidine
High- 3-Methylhistidine

Ratios:
High - Phenylalanine/Tyrosine
High- Glutamic Acid/Glutamine
High- a-ANB/Leucine
High- Tryptophan/LNAA

Anyone have a clue about this?
I have not been diagnosed with anything except b12/folate deficiency.
Have been trying methylation protocol. The tingles, zaps, sleep and cardiac symptoms are improved, but fatigue, muscle weakness and PEM and digestion issues are getting worse.
Any input would be appreciated as I'm at a loss and low on funds for medical consults.
 

Valentijn

Senior Member
Messages
15,786
The methylhistidines are a likely indication that you're burning muscle for fuel. So your Krebs cycle or the main pathways leading into it might be in bad shape.

Elevated glutamic acid might cause a "wired" sensation that can cause sleep and some cognitive problems. N-acetylcysteine might help bring that down, though sometimes glycine is needed as well.