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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Aescin - a most unusual response

R

ramakentesh

Senior Member
Messages
534
Recently my doctor ok'd the use of Horse Chestnut or aescin to combat dizziness from POTS. I took a minute dose and my BP went up to 197/106!
ive been thinking about this hypertensive response to a minute dosage of this herbal preparation.
it is reputed to act on serotonin receptors specific to the veins and via release of prostglandulins. The former has been found to be abnormal in CFS and through my own experience (supersensitivity to mild herbal SSRIs which suggested upregulated 5-HTa2 receptors at a guess) and the later has been implicated at least in a talk by Vanderbilt in the etiology of POTS. Interesting...
Low peripheral serotonin activity causing upregulation of serotonic receptors in the vasculature?
 
xrayspex

xrayspex

Senior Member
Messages
1,111
Location
u.s.a.
I was searching horse chestnut because I get Intracranial hypertension (ICH) from time to time esp if mess up my neck--and lying down can increase pressure--I have thought about trying diamox but meds and me don't usually agree
horse chestnut was recommended in the comment section of a blog on ICH as a natural alternative to diamox to lower pressure pain so that is quite paradoxical what happened to you

http://permanentheadache.blogspot.com/2009/09/day-260-intracranial-hypertension.html

https://www.drweil.com/vitamins-supplements-herbs/herbs/horse-chestnut/
 
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