Has anyone experienced this or does someone know the underlying mechanism? I started off on b12 with hydroxy & separate adenosyl lozenges. I noticed after the adenosyl a drop in energy but thought it was really odd. My ND gave me a lozenge that's 4000mcg methylcobalamin and 1000mcg adenosylcobalamin. Feel ok on 1 lozenge but 1.5 leaves me very fatigued in the body, achey. Feels just like PEM?