Review: 'Through the Shadowlands’ describes Julie Rehmeyer's ME/CFS Odyssey
I should note at the outset that this review is based on an audio version of the galleys and the epilogue from the finished work. Julie Rehmeyer sent me the final version as a PDF, but for some reason my text to voice software (Kurzweil) had issues with it. I understand that it is...
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Abnormal Chromogranin-A results?

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by Ocean, Jun 25, 2012.

  1. Ocean

    Ocean Senior Member

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    Anyone else have this test and get abnormal results? How high were your levels? Mine was only a little above the normal range.

    Do you know if this test, when not so high as to indicate a tumor, indicates anything about CFS? The only thing I could find on that was this passage, which from what I could understand has something to do with Celiac disease?
    http://www.ncf-net.org/forum/chromogranin.html
     
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  2. August59

    August59 Daughters High School Graduation

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    Upstate SC, USA
    That is a test I have never even heard of. What lab did you have done at? Was it a serum analysis?
     
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  3. Ocean

    Ocean Senior Member

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    Yes it was blood, just a regular lab, probably Labcorp. There is some info online about the test but I only found the one article tying it to CFS. I may have to redo it also as you are supposed to test when you are having symptoms I think, which I wasn't able to do.
     
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  4. bjl218

    bjl218 Brian Levine

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    Old post, but I was wondering what the outcome of this test was. My CgA just came back somewhat high. We’re redoing the test because I was taking Zantac, Amitriptyline, and biotin prior to doing this test
     
  5. Ema

    Ema Senior Member

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    It’s a marker fo MCAS and other inflammatory conditions but you are right to redo it because H2 blockers like Zantac can cause false positives.

    http://www.mastattack.org/2017/02/chromogranin-a/
     
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  6. bjl218

    bjl218 Brian Levine

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    So it looks like this was a false alarm. I re-did this test after being off of all meds and supplements for a week. My CgA went from 180 to 105 via Quest. Their reference range is 25-140 ng/mL.

    Looking back, I was also eating a fairly high histamine diet (lots of oysters and yogurt).

    Lots of contradictory information on the Web about this, but from what I've been able to gather, staying off those meds and supplements and sticking to a low-histamine diet would probably have lowered my CgA even more.

    Phew!
     

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