A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells https://www.nature.com/articles/s41467-017-01886-6 Hmm..A lot of helminth papers now "The ability of Hp-TGM to delay allograft rejection, and to inhibit all three major subsets of effector CD4+ T cells in vivo, also portends well for a therapeutic application of this new molecule. Recombinant Hp-TGM offers several advantages including scalable production, a definable mechanism of action and the opportunity for modification to reduce immunogenicity and optimise pharmacokinetic characteristics for pharmacological use. Furthermore, combinations of Hp-TGM with currently available immunomodulatory agents may further enrich future therapeutic strategies in which the directed manipulation of the different T cell subsets will offer resolution of inflammatory conditions of diverse aetiologies." Would anyone want to speculate whether this induction of regulatory T-cells by the TGF mimic would be good for people with CFS? Thanks.