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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. S

    Need advice on understanding my symptoms/condition

    @Valentijn regarding to the SNP info, you mentioned some of them with single letter (e.g only G) risk factor, if one of my two alleys has that letter, that means I had that mutation ?
  2. S

    Need advice on understanding my symptoms/condition

    I am taking B12 lozenges in the morning at 9am and keep it in my mouth until 11am. Folate is with empty stomach. I will try lowering both of them and see if that helps. I need to order folate 400 or 800mcg and 2000/1000mcg b12.
  3. S

    Need advice on understanding my symptoms/condition

    @Valentijn Thanks a lot for the information on SNPs, I will go through them. Also do you think Its helpful if I order methylation pathway panel ? The other thing is, I also felt little bit tired as the day goes and bit difficult to fall into sleep after started using B12 (compared to my...
  4. S

    Need advice on understanding my symptoms/condition

    But isn't elevated Homocysteine means B12/Folate deficiency as a scientific test and symptoms associated with that are related to Neurological ? IMO Treating that with B vitamins should fix elvated levels and methylation cycle and reduce the symptoms. (that is what happened with b12 supplements.)
  5. S

    Need advice on understanding my symptoms/condition

    I tried seeking health's Homocysteine X wich has B6, but it didn't help my symptoms.
  6. S

    Need advice on understanding my symptoms/condition

    Thank you for the suggestion Valentijn. What do you think about the reason for my homocysteine levels elevated ? I saw in the wiki that the optimal level should be < 11.4. I thought my issue or elevated homocysteine is due to some of MTR/MTHFRs are +/- and A1298C is +/+. Btw I eat lot of...
  7. S

    Need advice on understanding my symptoms/condition

    Hello, I am newbie to this group. I would like to first say that, I really impressed with the amount of information/experiences you guys share and it helped me understand lot of things. I wouldn't have restarted my B12 and Folic acid supplements again in proper way, if I wouldn't find this...