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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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    Deep depression, despair, paranoia and need for isolation

    Hey folks just wanted to say thanks for the responses and provide an update. I've taken a few days off the protocol for now (including donors) and still having some depression oddly enough - though nothing requiring me to seek professional help mind you. I think I've kicked up some emotions from...
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    Deep depression, despair, paranoia and need for isolation

    I recently started a basic methylation protocol as I try to recover from a damaged liver and the oxidative stress that accompanies this. It was working great for a couple weeks @ methylcobalamin-1g and 800mcg l-methylfolate. Started seeing life a lot more clearly, and my libido improved. All of...
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    First time poster - Curcumin - what is this?

    Thank you very much for the responses folks. I'm going to try a better brand of curcumin to at least rule that piece out. Will report back...
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    First time poster - Curcumin - what is this?

    @JES Apologies I have updated the spelling. @Cheesus, I have tried it with black pepper though my brand I have in hand doesn't seem to have anything to help w/ bio-availability (including as you mention bioperine). Didn't seem to make a difference. But as you mention the anger link is...
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    First time poster - Curcumin - what is this?

    Hi there, Happy to say long time lurker, first time poster... a wealth of knowledge on this forum and I had to get on. Hoping for some help with a key finding along my road to recovery. I'm going to try to make my background short. My liver/gallbladder were both in horrible shape, still...