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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. V

    High S-adenosyl homocysteine but low homocysteine - please help me understand!

    Thanks for the input Valentijn. May I ask where your information comes from and how sure you are in the statement? Do the Yasko/Genie variants have any other impact at all? Why are they included by Genie and Yasko? Thanks in advance for your contribution!
  2. V

    High S-adenosyl homocysteine but low homocysteine - please help me understand!

    I know this is old but hope andocobo is still around to respond. I am Homozygous for all the AHCY mutations that Genetic Genie tests from 23andMe and suspect having low AHCY activity. I have not had SAMe/SAH test done yet as I am not in the US currently and the local market does not offer the...