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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. C

    Biochemistry input on sleep question?--Orexin

    I just started trial Belsomra 7 dys ago. Absolutely fantastic. I used to start with melatonin. .. Then benadryl. .. Then codeine. Even then I would wake up at 2am. Could NEVER touch caffeine or pay the price of no sleep for 2 or more days. Motion sickness pills work sometimes but leave you...
  2. C

    Fixed my night sleep issue but now have Narcolespy?

    Just a note. It looks like you made a big jump from pregnenolone to prednisone ! Pregnenolone is a mother hormone to over 200 sub hormones. Pregnenolone is generated in the body from vit D. It does help some people sleep. Use sparingly and creep up on it. Your body can choose which direction...