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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Search results

  1. U

    Testing for OverMethylation?

    I have considered BH4 previously as I think I have a number of issues around that cycle. However, I'm not sure if it is available here in the UK? I've ordered Coenzymated B-3, FMN, Calcium d-glucarate (for estrogen metabolism), ubiquinol/PQQ (energy), activated charcoal/mag oxide (Ammonia)...
  2. U

    Testing for OverMethylation?

    Thanks for commenting @TheChosenOne. I notice we have similar snps (in as much that our main problem perhaps isn't MTHFR/MTRR). I am currently playing (I think that's the best description) with methyl donors in the early part of the day and methyl 'absorbers' later in the day. Currently...
  3. U

    Testing for OverMethylation?

    Hi, What experience/opinions do you guys have with testing relating to methylation? Based on long standing symptoms and recent methyl supplement reactions, I now suspect I am an over-methyator. Symptoms - I have an absence of seasonal allergies, high sensitivity to perfumes, high levels of...
  4. U

    Please Comment on my Methylation Profile

    Hi dulcinea, It would be worth updating each other on progress given our similar snps. I am going on holiday shortly (sadly bringing lots of methylation reading with me!) so I might not be able to post for a week or so, but after that I will update my experiences as I appreciate others doing...
  5. U

    Please Comment on my Methylation Profile

    After a week or so of feeling more energetic, happier and clear headed I started to lose that feeling. It was replaced with low energy and even lower mood. Now things have settled down a bit, I can reflect and say that Metafolin and Mb12 make me uncomfortably edgy and tense. Going forward...
  6. U

    Please Comment on my Methylation Profile

    Thanks you all very much for your replies. Thanks for putting my mind at rest regarding CBS. @JaimeS - I had a quick look at your blog JaimeS and had to close it down for more careful read tonight (it looks like a serious piece of work). @TheChosenOne - I now understand why I am sensitve...
  7. U

    Please Comment on my Methylation Profile

    Hi All, I have only posted once here, regarding what I thought was a strange methylation experience. In summary, I had a great reaction (lots of energy, metter mood, more confidence ) to a Coenzymated B Complex (though later I noticed that it did contain some Folic Acid). I increased the dose...
  8. U

    My (Strange?) Methylation Experience

    Hi @JaimeS I know what you mean by betrayal. A herb is supposed to balance out hormones and/or neurotransmitters and it completely sends one or more out of whack! We keep hearing about paradoxical reactions, I guess it's yet another one? I'm currently only taking 10mg of Citalopram every...
  9. U

    My (Strange?) Methylation Experience

    @Mary - Thanks for the tip. I wondered why people were doing that! @JaimeS - I still have some glycerrhiza. My cortisol test came back ok, but I have symptoms of low morning cortisol, so I might try it for a few days. I have never heard of cimicifuga, I suspect low dopamine as acetyl...
  10. U

    My (Strange?) Methylation Experience

    Thank you all very much for your replies. It has given me a lot to think about. Taking each on in turn: JaimeS - Wow, I wasn't expecting a reply like that. A great analogy and has me thinking in a different way. I support my adrenals, but you have reinforced that for me. I will also start...
  11. U

    My (Strange?) Methylation Experience

    Hi Everyone, Firstly I’d like to thank each and every poster here for posting their experiences. This collective knowledge is invaluable. Like many here I have had many years of baffling ill health. I have been though Candida diets, Adrenal/Endocrine support and Mercury Chelation amongst...