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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. R

    what's the deal with 23andme?

    You should also be aware that 23andMe, as of late 2013, is using their new v4 chip. Instead of 967,000 SNPs included on the old v3 chip, the new v4 only has 602,000 SNPs. There is still loads of data to look through, obviously, but some things are missing. For example, I was hoping to get a...
  2. R

    Do My Genes Explain why Methyl. Doesn't Work??

    Hi JAH, I have the same homozygous CBS mutation that you have and four COMT +/+ SNPs. What I can tell you, from my own experience, is that methylcobalamin and methylfolate make me very agitated. Like you, I also have elevated ammonia and all of my urea cycle amino acids are deficient. Red