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I had been taking low dose naltrexone and seeing benefits in my chronic pain. Before I started taking it I was on an immunosuppressant (cortisone) that caused a latent HPV infection to come back aggressively (the cortisone is out of my system now). I was advised by my Gyn to stop taking the naltrexone (out of concern that anything affecting the immune system might make it harder for me to clear the HPV), and I’ve been off it for four days. My nerve pain is so bad today, now I’m pretty confident the naltrexone was helping. I want to go back on the naltrexone for pain, but I am afraid it’s suppressing my immune system, and I obviously don’t want to have HPV symptoms hanging around. I’m also worried that I need to start at a lower dose again to work my way up to the 3 mg I was at 4 days ago. Does anyone have advice? I’m still confused as to what naltrexone does to the immune system. I have a lot of conflicting immune problems, such as not fighting off illness but also things like eczema and allergies, all of which have been flaring lately. It seems like my immune system is suppressed and overactivated at the same time?