I have read where if one has igg antibodies that just shows you have been exposed to the virus at some time. Small minority of drs think if the igg levels are above a certain level its a chronic infection. Also if igg antibodies increase over time, drs are more inclined to think the virus is chronic more so then just high titres.
This point kept me from getting care sooner. I had over 10 doctors dismiss my IgG antibodies, saying "all that shows is that you had them in the past." When I finally saw a top CFS specialist, he said "...that's what we were taught in med school, but when they're high, like yours, you have a chronic, recurrent infection."
Interestingly, though I knew about 4 other infections, my EBV infection was difficult to find. All prior EBV tests had been negative before I finally had very high VCA and PCR tests, so your doc was wise to run the full panel of EBV tests.
High total lymphocytes and or high or low neutrophils are seen as an active infection of some sort. High cd8 t lymphocytes are commonly seen in ebv and cmv infections.
This, too can be misleading. I learned I have a seriously underactive immune system that's not reacting to my infections, so my lymphs, neutrophils, and CD8s are always normal, even with active CMV, EBV, and HHV6.
If you saw a dr who regularly treats cfsme patients than they possibly would give you antivirals for a few months and see how you go.
Once my doctors finally figured out I had EBV, I was put on a high dose of valganciclovir and LDN and expect to be on them for many months, with liver monitoring. I'm also in the process of getting IVIG approved.
You should be investigated further for other immune defiencies or other possible infections.
This is important. Even though we knew I had infections and was doing a lot for them, my body wasn't responding as the load of infections I have is huge and my immune system was too weak to fight, even with lots of support.
Getting all the immunoglobulins tested along with subclasses is important, along with CDs, NKs, etc.
So, I wasted about a year not knowing the full scope of the problem I was tackling. I was staying functioning at a higher level than I would have otherwise, but the infections weren't going away.
And different infections may require different treatments.
The other thing that was helpful was being tested for adrenergic and muscarinic autoantibodies. Apparently, infections can keep stressing our systems and causing an autoimmune response. We'll watch them as I go through treatment and they may dictate the need for further treatment, like Rituximab.