From Naviaux's paper here
I know it's a few months old now but this is a pretty big finding right? Questions...
The dominant finding from the pathway analysis was that sphingolipid abnormalities constituted close to 50% of all of the metabolic disturbances associated with CFS in both males and females.
I know it's a few months old now but this is a pretty big finding right? Questions...
- Are there any other illnesses which have similarly low levels of Sphingolipids?
- Is there a way to replace lost Sphingolipids/ceramides and would doing so have a positive impact for ME/CFS patients?
- How do low sphingolipids relate to sugar metabolism? Are they a consequence or cause of PDH being blocked?