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Treating Acidosis with Erythromycin

SB_1108

Senior Member
Messages
315
Just wondering if anyone knew of any medical studies about treating acidosis with erythromycin?

KDM is my doctor and he recently suggested it for elevated lactic acid issues.
Dr. Sarah Myhill also suggests it for acidosis:
http://www.drmyhill.co.uk/wiki/Ferm...nd_CFS#Treatment_of_high_Streptococcus_levels

I've also found this article about treating ME/CFS patients with erythromycin to reduce lactate producing bacteria (like Strep) and improve sleep: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688574/

Anything else?

I thought that penicillin was the first choice for lactic acid producing bacteria?
 
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SB_1108

Senior Member
Messages
315
Not sure? How do you tell them apart?

My acidosis symptoms began after antibiotics and it is worsened by carbs and certain probiotics. Major digestive correlation!
 

kangaSue

Senior Member
Messages
1,851
Location
Brisbane, Australia
Not sure? How do you tell them apart?

My acidosis symptoms began after antibiotics and it is worsened by carbs and certain probiotics. Major digestive correlation!
Good question, I'm not sure of the answer though. Pain is the usual reaction to hypoxia and L-lactate might be elevated in the blood (the liver is usually very efficient at mopping it up) but pain is the result of a lot of other insults other than ischemia.

Are you going on symptoms alone or have you tested to elevated lactate levels? People with ME/CFS can have elevated levels of either L-lactate or D-lactate, the latter able to cause brain fog to and some people get elevated levels of D-lactate from eating carbs.

SIBO from taking antibiotics can cause similar symptoms without elevating lactate levels.
 

outdamnspot

Senior Member
Messages
924
Not sure? How do you tell them apart?

My acidosis symptoms began after antibiotics and it is worsened by carbs and certain probiotics. Major digestive correlation!

what are the symptoms you associate with acidosis?
 

SB_1108

Senior Member
Messages
315
what are the symptoms you associate with acidosis?

I can't have any carbs at all - no potatoes, bread, nuts, fruit, etc - because I begin to experience acidosis symptoms pretty severely. I become completely exhausted, unable to move or speak, gasping for air - feeling like I'm dying because I can't get enough oxygen. Even my daily cup of coffee has become a problem. My food allergies in general are completely out of control. I think gut fermentation is a huge part of this problem. I'm down to eating about the same five foods on rotation.

My gastroenterologist wanted me to try Amoxicillin so for the last three days I did that... it hasn't been good. I won't be taking it tomorrow.
 

SB_1108

Senior Member
Messages
315
Are you going on symptoms alone or have you tested to elevated lactate levels? People with ME/CFS can have elevated levels of either L-lactate or D-lactate, the latter able to cause brain fog to and some people get elevated levels of D-lactate from eating carbs.

SIBO from taking antibiotics can cause similar symptoms without elevating lactate levels.

Yes I'm going off symptoms alone. I have been diagnosed with SIBO.
Have any suggestions? :(
 

kangaSue

Senior Member
Messages
1,851
Location
Brisbane, Australia
Yes I'm going off symptoms alone. I have been diagnosed with SIBO.
Have any suggestions? :(
Maybe get tested for elevated levels of D-lactate. Some people with ME/CFS find that carbs produce elevated levels of D-lactate, the same situation can occur with Short Bowel Syndrome which is a malabsorption problem.

My GI motility specialist said to me to assume that you have SIBO too in anyone having chronic delayed motility problems and suggested rotating between different antibiotics for 10 days every month for 6 - 12 months (amoxycillin, doxycycline and metronidazole). I'm hard pressed to tolerate them for five days.

Rifixamin is often suggested for SIBO but studies don't find it any better than the combo of standard antibiotics. I have seen it suggested by several people that combining rifixamin with metronidazole was effective when rifixamin alone didn't help with symptoms.