Cheshire
Senior Member
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Consecutive eligible patients (n=264) who met diagnostic criteria for chronic fatigue syndrome (CFS) or post-cancer fatigue (PCF) were evaluated with self-report measures of fatigue, functional capacity, and mood disturbance, at baseline, end-treatment (12-weeks), and follow-up (24-weeks). A semi-structured
interview recording the same parameters was conducted pre- and post-treatment by an independent clinician. Primary outcome (fatigue) was analysed by repeated measures ANOVA and predictors of response was analysed by logistic regression
The intervention produced sustained improvements in symptom severity and functional capacity. A substantial minority of patients (35%) gained significant improvement, with male gender and higher pain scores at baseline predicting non-response. A small minority of patients (3%) worsened.
Conclusions:
The manualised protocol of integrated CBT and GET was successfully implemented confirming the generally positive findings of clinical trials. Assessment and treatment protocols are available for dissemination to allow standardised management. The beneficial effects described here provide the basis for ongoing studies to further optimise the intervention and better identify those most likely to respond
Andrew Lloyd participated
Some of the people involved are from the "Fatigue Clinic, Lifestyle Clinic"
No objective measures (Absurd, even from a psychiatrist perspective: Who would accept a clinical trial for anorexia nervosa without any measurment of weight gain and be satisfied with answers to questionnaires saying the patients feel they have gained weight?)
No control group (from what I get)
http://sci-hub.cc/10.1111/imj.13251
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