Bob
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Scientists discover 17 genetic variations that raise risk of depression
Research involved 300,000 people of European ancestry and could lead to better understanding of the condition
https://www.theguardian.com/science...-of-depression?CMP=twt_a-science_b-gdnscience
Research involved 300,000 people of European ancestry and could lead to better understanding of the condition
https://www.theguardian.com/science...-of-depression?CMP=twt_a-science_b-gdnscience
To unpick possible genetic associations, the researchers examined data collected by the consumer genetic testing company 23andme. Of the 300,000 people studied, 75,607 self-reported a clinical diagnosis of depression or were receiving treatment for the condition.
By comparing the frequency of common genetic variations in the people with depression compared to those without, the scientists discovered two genomic regions associated with the condition, one of which has previously been linked to epilepsy and intellectual disability.
Further analysis, including 23andme data from another 150,000 individuals, as well as clinical data from a worldwide multi-institutional collaboration involving nearly 19,000 individuals, threw up more results, with scientists identifying 17 genetic variants in 15 genome regions associated with depression. The findings are published in the journal Nature Genetics.