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Hi all, I've been a long time lurker and after experimenting for a full year with supplements I thought I had everything figured out, but recently I've been having problems with p5p.
I've been taking 50mg of p5p in the morning with coffee and l-theanine, and it's given me a massive boost in energy, verbal fluidity and sociability. More recently (past two months) I've been dosing it a second time in the afternoon at 25mg and it immediately leaves me in a spacey haze. I feel mentally slower, brain fog sets in and a general sense of mental fatigue takes over me. I didn't make the connection until I read that p5p might be dangerous for those with CBS and MAO-A mutations, both of which I have. I have also re-introduced guacamole and sour cream into my diet after a while of intolerance.
Can the P5P be upsetting my CBS and MAO-A mutation? What's the connection between these SNP's and p5p?
As a side note, I've also started dosing calcium at 1G but it's been giving me depression. A few studies point to how it raises MAO-A within the body but I'm feeling bouts of rage and the typical symptoms of MAO-A deficiency so it might be doing more harm than good. I also have a GAD1 mutation. What's everyone's consensus on dosing calcium?
Thank you
I've been taking 50mg of p5p in the morning with coffee and l-theanine, and it's given me a massive boost in energy, verbal fluidity and sociability. More recently (past two months) I've been dosing it a second time in the afternoon at 25mg and it immediately leaves me in a spacey haze. I feel mentally slower, brain fog sets in and a general sense of mental fatigue takes over me. I didn't make the connection until I read that p5p might be dangerous for those with CBS and MAO-A mutations, both of which I have. I have also re-introduced guacamole and sour cream into my diet after a while of intolerance.
Can the P5P be upsetting my CBS and MAO-A mutation? What's the connection between these SNP's and p5p?
As a side note, I've also started dosing calcium at 1G but it's been giving me depression. A few studies point to how it raises MAO-A within the body but I'm feeling bouts of rage and the typical symptoms of MAO-A deficiency so it might be doing more harm than good. I also have a GAD1 mutation. What's everyone's consensus on dosing calcium?
Thank you