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California researchers found that analyzing cell-bound complement activation products (CB-CAPs) ably distinguishes between systemic lupus erythematosus (SLE) and fibromyalgia (FM), and complements current test methods.
Whereas fibromyalgia and lupus might share non-specific symptoms, the two diseases have a radically different underlying cause. Lupus is primarily an inflammatory autoimmune condition, while fibromyalgia is not, and the treatment and prognosis differ accordingly.
Many lupus patients are mistakenly diagnosed with fibromyalgia, however, when they present with symptoms that are non-specific, and do not fulfill formal classification criteria of lupus.
Current laboratory tests include a number of lupus-specific autoantibodies, and antinuclear antibody (ANA) is frequently used. Around 95 percent of all lupus patients test positive for ANA, but the antibody is also found in 14 percent of the general population and 15 percent to 25 percent of fibromyalgia patients. Other tests also suffer from poor sensitivity or specificity.
cont'd
http://fibromyalgianewstoday.com/2016/03/07/cb-caps-assay-can-distinguish-between-lupus-and-fibromyalgia/?utm_source=FM E-mail List&utm_campaign=d285d03f6c-RSS_WEEKLY_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_466e2e0f56-d285d03f6c-71455897
Whereas fibromyalgia and lupus might share non-specific symptoms, the two diseases have a radically different underlying cause. Lupus is primarily an inflammatory autoimmune condition, while fibromyalgia is not, and the treatment and prognosis differ accordingly.
Many lupus patients are mistakenly diagnosed with fibromyalgia, however, when they present with symptoms that are non-specific, and do not fulfill formal classification criteria of lupus.
Current laboratory tests include a number of lupus-specific autoantibodies, and antinuclear antibody (ANA) is frequently used. Around 95 percent of all lupus patients test positive for ANA, but the antibody is also found in 14 percent of the general population and 15 percent to 25 percent of fibromyalgia patients. Other tests also suffer from poor sensitivity or specificity.
cont'd
http://fibromyalgianewstoday.com/2016/03/07/cb-caps-assay-can-distinguish-between-lupus-and-fibromyalgia/?utm_source=FM E-mail List&utm_campaign=d285d03f6c-RSS_WEEKLY_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_466e2e0f56-d285d03f6c-71455897