homozygous:
MAO-A TT ++
VDR-Taq AA ++
MTHFR C677T ++
heterozygous:
COMT V158M AG
COMT H62H CT
MTRR A66G AG
MTRR K350A +-
BHMT-08 CT
CBS C699T
CBS A360A
This is all very mind-boggling for me. It caused my so much stress when I first received the results I had to step away from it for a few months. I have been taking methyl-folate (400 mcg) and methyl B12 since July of last year, though.
So....
VDR-Taq++ compined with COMT +- equals moderate need for dopamine/methyl donors, however some of my COMT genes are --, mean HIGH need for dopamine/ methyl donors. I do have symptoms of ADHD, so maybe it could be attributed to this?
I take 2000 IU of D3. I also take phosphitidyl serine and eat dark chocolate, all of which are methyl donors. I do well with L-theanine and melatonin (methyl donors) Methyl-B12 should be good for me, right? However, the big issue hear is that methyl-folate is supposed to cause issues for the MAO-A ++ gene. But on the other hand, isn't metyl-folate extremely important for me since I'm homozygous MTHFR C677T? Like I said I have been taking methyl-folate in a low dose (400 mcg) for months and do well on it. I also eat a lot of vegetables that contain it. However, I tried increasing to 800 mcg, and felt like I had been hit by a truck and didn't feel right for weeks. I reduced back to 400 mcg. So the question is, should I keep trying to slowly increase my methy-folate because of MTHFR and VDR-taq, or keep it at 400 mcg because of MAO-A?
Interestingly, I had off-the-charts high levels of B12 and folate before I started either of these supplements so it seems my body is not very good at utilizing them.
I'm pretty sure I'm OCD, although I don't see a therapist. That seems appropriate for an MAO-A defunct. Prozac and 5-HTP were a nightmare for me, which makes sense if I'm unable to break down serotonin. Can lithium orotate help with the defunct?
Is a heterozygous CBS mutation a big deal? My homocysteine isn't super-high or low (7). The idea of not being able to eat garlic, onions, or eggs is devastating to me because I love to cook and these foods are the foundation of cooking. I also had an eating disorder and limiting any food causes enormous stress for me which is more unhealthy than anything, I'm sure
I need help relating how all these malfunctions interact with each other... please help! I guess my biggest question is the methyl-folate needed for MTHFR and VDR-taq but not advised for MAO-A......
MAO-A TT ++
VDR-Taq AA ++
MTHFR C677T ++
heterozygous:
COMT V158M AG
COMT H62H CT
MTRR A66G AG
MTRR K350A +-
BHMT-08 CT
CBS C699T
CBS A360A
This is all very mind-boggling for me. It caused my so much stress when I first received the results I had to step away from it for a few months. I have been taking methyl-folate (400 mcg) and methyl B12 since July of last year, though.
So....
VDR-Taq++ compined with COMT +- equals moderate need for dopamine/methyl donors, however some of my COMT genes are --, mean HIGH need for dopamine/ methyl donors. I do have symptoms of ADHD, so maybe it could be attributed to this?
I take 2000 IU of D3. I also take phosphitidyl serine and eat dark chocolate, all of which are methyl donors. I do well with L-theanine and melatonin (methyl donors) Methyl-B12 should be good for me, right? However, the big issue hear is that methyl-folate is supposed to cause issues for the MAO-A ++ gene. But on the other hand, isn't metyl-folate extremely important for me since I'm homozygous MTHFR C677T? Like I said I have been taking methyl-folate in a low dose (400 mcg) for months and do well on it. I also eat a lot of vegetables that contain it. However, I tried increasing to 800 mcg, and felt like I had been hit by a truck and didn't feel right for weeks. I reduced back to 400 mcg. So the question is, should I keep trying to slowly increase my methy-folate because of MTHFR and VDR-taq, or keep it at 400 mcg because of MAO-A?
Interestingly, I had off-the-charts high levels of B12 and folate before I started either of these supplements so it seems my body is not very good at utilizing them.
I'm pretty sure I'm OCD, although I don't see a therapist. That seems appropriate for an MAO-A defunct. Prozac and 5-HTP were a nightmare for me, which makes sense if I'm unable to break down serotonin. Can lithium orotate help with the defunct?
Is a heterozygous CBS mutation a big deal? My homocysteine isn't super-high or low (7). The idea of not being able to eat garlic, onions, or eggs is devastating to me because I love to cook and these foods are the foundation of cooking. I also had an eating disorder and limiting any food causes enormous stress for me which is more unhealthy than anything, I'm sure
I need help relating how all these malfunctions interact with each other... please help! I guess my biggest question is the methyl-folate needed for MTHFR and VDR-taq but not advised for MAO-A......