ppodhajski
Senior Member
- Messages
- 243
- Location
- Chapel Hill, NC
Anyone like me? I found that my SNPs make me very sensitive to eating any fats, but very sensitive to my balance of omega 3 vs omega 6. All the research points to the rare alleles creating the faster enzyme and therefor creates more inflammatory or anti-inflammatory prostoglandins, depending of course on the balance of omega 3 vs omega 6.
There is a ton of well documented work on how these SNPs can effect mood, cardiovascular, and other inflammatory conditions. My family has a strong history of all of them. I have been on a low fat, fish only, diet and it makes me feel great. The minute I go on a higher fat diet I get depressed and symptoms of my CFS comes back.
Also, every child whose SNPs I have for Autism have these rare alleles. I am not saying it is a cause, but I have Aspergers and I think it might play a role.
http://www.austinpublishinggroup.com/nutrition-metabolism/fulltext/ajnm-v2-id1017.php
"There are over 100 genes of known chromosomal loci involving phospholipid metabolism, and over half of them are associated with various mental disorders [1]. Many such mental disorders are represented in family histories of children with ASD, and are often experienced by ASD patients as comorbidities. Of particular interest is the desaturase gene cluster involved in the conversion of essential fatty acids into end products critical to brain function."
My SNPs
FADS1 Risk Allele
rs174549 A
rs174550 C
rs174546 T
rs174547 C
rs174548 G
rs174556 T
FADS2
rs482548 T
rs174575 G
rs174570 T
rs498793 A
rs1535 G
rs174576 A
There is a ton of well documented work on how these SNPs can effect mood, cardiovascular, and other inflammatory conditions. My family has a strong history of all of them. I have been on a low fat, fish only, diet and it makes me feel great. The minute I go on a higher fat diet I get depressed and symptoms of my CFS comes back.
Also, every child whose SNPs I have for Autism have these rare alleles. I am not saying it is a cause, but I have Aspergers and I think it might play a role.
http://www.austinpublishinggroup.com/nutrition-metabolism/fulltext/ajnm-v2-id1017.php
"There are over 100 genes of known chromosomal loci involving phospholipid metabolism, and over half of them are associated with various mental disorders [1]. Many such mental disorders are represented in family histories of children with ASD, and are often experienced by ASD patients as comorbidities. Of particular interest is the desaturase gene cluster involved in the conversion of essential fatty acids into end products critical to brain function."
My SNPs
FADS1 Risk Allele
rs174549 A
rs174550 C
rs174546 T
rs174547 C
rs174548 G
rs174556 T
FADS2
rs482548 T
rs174575 G
rs174570 T
rs498793 A
rs1535 G
rs174576 A