South
Senior Member
- Messages
- 466
- Location
- Southeastern United States
Caprylic acid supplements, widely sold in vitamins stores and online, are popular among people who are trying to reduce candida / yeast infections. (For those who need a study for this sentence, there are a few, the only one I had time to dig up for that right now is: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC278470/ )
Ok, so on to the point of my post:
I saw some studies that, I think, say that caprylic acid loosens the junctions of gut cells. The studies portray this as a good thing for improving absorption of prescription drugs taken at the same time, or for the absorption of nutrients. But loosening the junctions of the gut cells isn't a good thing if we already have a gut that is too leaky -- an overly permeable gut.
(and before someone gets into a battle over whether leaky gut exists, google "intestinal permeability" and read some of the science behind it)
I'm not the best at reading sciency lingo, so maybe I misunderstood. Here's one of the studies:
http://link.springer.com/article/10.1023/A:1015840921203?LI=true
Toward the bottom of the text, there's text stating that Caprylic acid increased the permeability of the Paracellular pathway across the Rat Colon Epithelium.
The language in that study is awkward, so here's another one that talks about a similar effect, from sodium caprate (which isn't caprylic acid): when I read both studies and compare the lingo, it seems that caprylic makes gut junctions more permeable.
http://link.springer.com/article/10.1023/A:1018909210879
Ok, so on to the point of my post:
I saw some studies that, I think, say that caprylic acid loosens the junctions of gut cells. The studies portray this as a good thing for improving absorption of prescription drugs taken at the same time, or for the absorption of nutrients. But loosening the junctions of the gut cells isn't a good thing if we already have a gut that is too leaky -- an overly permeable gut.
(and before someone gets into a battle over whether leaky gut exists, google "intestinal permeability" and read some of the science behind it)
I'm not the best at reading sciency lingo, so maybe I misunderstood. Here's one of the studies:
http://link.springer.com/article/10.1023/A:1015840921203?LI=true
Toward the bottom of the text, there's text stating that Caprylic acid increased the permeability of the Paracellular pathway across the Rat Colon Epithelium.
The language in that study is awkward, so here's another one that talks about a similar effect, from sodium caprate (which isn't caprylic acid): when I read both studies and compare the lingo, it seems that caprylic makes gut junctions more permeable.
http://link.springer.com/article/10.1023/A:1018909210879
Last edited:
