Also I heard it is not water soluble so you can't crush it and put on water like other things.
It is water soluble; the liquid form of Valcyte consists of Valcyte dissolved in water, with some preservatives added.
You can use water to dilute Valcyte to arbitrarily small doses. Preservatives aren't needed if you consume it within a reasonable amount of time - I would think that it would be plenty safe to store the unused portion for a month, refrigerated.
@zzz is the person cutting it down to that dose.
Yes, I started using low dose Valcyte myself and am in touch with a number of others who are doing the same.
The latest evidence seems to show that 1/64th of a tablet of Valcyte per day (7 mg) provides all of the benefits of a full dose with almost none of the risk. Doses don't even have to be daily; if negative side effects occur, spacing the doses out gets rid of them. The pharmacology behind this is all rather complex; I plan to cover it in detail in a separate thread.
Low dose Valcyte has two powerful beneficial effects: microglial anti-inflammatory and immunomodulatory. Between the two of these, it appears that virtually all of the symptoms of ME/CFS can be addressed. In particular, the immunomodulatory effects of low dose Valcyte appear to be stronger than those of standard dose Valcyte, as with low dose Valcyte the negative pro-inflammatory negative side effects are far less than those of the standard dose Valcyte. These pro-inflammatory side effects interfere with Valcyte's benefits.
So to give a practical example, the low dose Valcyte regimen that I am currently taking has succeeded in eliminating a bacterial gut infection that antibiotics had only limited success against.
From this point of view, with low dose Valcyte, Famvir might not even be necessary. Famvir only has action against the virus, and requires cooperation from an immune system that happens to defective with us; such cooperation is not always forthcoming. Low dose Valcyte gets the immune system working properly, and should allow it to drive the virus into remission on its own.
As far as cutting the pill goes, there appears to be absolutely no reason not to do this. The only rationale for not cutting the pill seems to be that to get the full antiviral benefits of Valcyte, the full dose should be taken. This rationale does not apply to low dose Valcyte. Valcyte itself does not appear to be any more toxic than other pills. Dr. Montoya has told his patients that it is fine to cut the pills.