picante
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Yes, it's another thread on riboflavin! I've found some information that's new to me.
A concise list of B2 functions from this site:
From the main reference book cited for the list above, Advanced Nutrition and Human Metabolism:
A concise list of B2 functions from this site:
Functions:
As part of (FMN) and (FAD) riboflavin is involved in oxidation and reduction reactions of energy metabolism:
Anabolic, catabolic, and conversion processes
- Active in the electric transport chain in mitochondria: a major site of energy metabolism
- Oxidation of pyruvate: a product of amino acid, glycerol and glucose metabolism during the production of energy
- Fatty acid oxidation and the production of energy
- Synthesis of sphingosine a component of sphingolipids required in cell membranes, an anabolic process
- With Zanthine oxidase enables the catabolism of purine (a nucleic acid) in your liver
- With aldehyde oxidase enables the conversion of aldehydes to pyridoxic acid
- With aldehyde oxidase enables the conversion of retinal (vitamin A) to retinoic acid
- Participates in vitamin B6 metabolism
- Participates in the synthesis of the active form of folate
- Participates in the synthesis of niacin from tryptophan
- Enables the catabolism of choline
- Involved with monoamine oxidase in the metabolism of neurotransmitters (dopamine)
- Involved with monoamine oxidase in the metabolism of tyramine (may have a role on the central nervous system in some people) and histamine (involved in local immune responses)
- With glutathione reductase enables the reduction of Glutathione disulphide to Glutathione (GSH: an antioxidant)
From the main reference book cited for the list above, Advanced Nutrition and Human Metabolism:
Synthesis of FMN and FAD appears to be influenced by endproduct inhibition and hormones including ACTH, aldosterone, and the thyroid hormones, all of which accelerate the conversion of riboflavin into its coenzyme forms, apparently by increasing the activity of flavokinase.