Marco
Grrrrrrr!
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This is an interesting new article from Cort :
http://www.cortjohnson.org/blog/201...uropathy-found-in-fibromyalgia-patients-eyes/
Now that we have several objective findings of small fibre (peripheral) neuropathy in around 50% of fibro patients it suggests that fibro may not be solely a central pain condition (although the researchers have been a little coy to date as to whether these findings suggest misdiagnosis, a co-morbid condition or represent a clue to the underlying pathology).
One drawback of investigating small fibre neuropathy is the need to tale a skin punch biopsy. However small fibre neuropathy also effects nerves in the cornea (and the autonomic nervous system) and neuropathy can be detected non-invasively by corneal microscopy.
Given repeated findings of autonomic dysfunction in ME/CFS with 'something' possibly acting as a peripheral signal, this non-invasive test strikes me as worth a pilot study at least.
http://www.cortjohnson.org/blog/201...uropathy-found-in-fibromyalgia-patients-eyes/
Now that we have several objective findings of small fibre (peripheral) neuropathy in around 50% of fibro patients it suggests that fibro may not be solely a central pain condition (although the researchers have been a little coy to date as to whether these findings suggest misdiagnosis, a co-morbid condition or represent a clue to the underlying pathology).
One drawback of investigating small fibre neuropathy is the need to tale a skin punch biopsy. However small fibre neuropathy also effects nerves in the cornea (and the autonomic nervous system) and neuropathy can be detected non-invasively by corneal microscopy.
Given repeated findings of autonomic dysfunction in ME/CFS with 'something' possibly acting as a peripheral signal, this non-invasive test strikes me as worth a pilot study at least.