daniariete2000
Senior Member
- Messages
- 118
Hi,
I read this interesting blog http://drfairchild.blogspot.it/2013/10/mthfr.html?m=1 and my attention was on that point:
"
MTHFR 677 measures:
Avoid folic acid. Use L methylfolate (metafolin) or folinic acid instead, N acetyl cysteine, SAMe, and B12 (methylcobalamin or hydroxocobalamin or adenosylcobalamin).
Methylfolate is best absorbed on an empty stomach. Use only the L form and avoid the D form.
Consider eliminating gluten and dairy.
MTHFR 1298 measures:
BH4 levels can be best increased by 5-methyltetrahydrofolate (5-MTHF) and vitamin C (ascorbic acid). 5-MTHF helps scavenge peroxynitrite (ONOO) and increases vascular BH4 and BH4/total biopterin ratio.
Supplementation of magnesium, copper, vitamin B6, SAMe, B12 (as hydroxocobalamin), vitamin A, a-ketoglutaric acid, tyrosine and 5HTP may also be helpful.
Other helpful measures may include eating a lower protein diet (as ammonia depletes BH4), limiting L-phenylalanine intake.
Those who are compound heterozygous can combine helpful measures for both MTHFR 677 and 1298. "
My question is :
Since I'm Heterozygous for A1298C , why I should avoid methylcobalamin ?
Thanks
Daniele
I read this interesting blog http://drfairchild.blogspot.it/2013/10/mthfr.html?m=1 and my attention was on that point:
"
MTHFR 677 measures:
Avoid folic acid. Use L methylfolate (metafolin) or folinic acid instead, N acetyl cysteine, SAMe, and B12 (methylcobalamin or hydroxocobalamin or adenosylcobalamin).
Methylfolate is best absorbed on an empty stomach. Use only the L form and avoid the D form.
Consider eliminating gluten and dairy.
MTHFR 1298 measures:
BH4 levels can be best increased by 5-methyltetrahydrofolate (5-MTHF) and vitamin C (ascorbic acid). 5-MTHF helps scavenge peroxynitrite (ONOO) and increases vascular BH4 and BH4/total biopterin ratio.
Supplementation of magnesium, copper, vitamin B6, SAMe, B12 (as hydroxocobalamin), vitamin A, a-ketoglutaric acid, tyrosine and 5HTP may also be helpful.
Other helpful measures may include eating a lower protein diet (as ammonia depletes BH4), limiting L-phenylalanine intake.
Those who are compound heterozygous can combine helpful measures for both MTHFR 677 and 1298. "
My question is :
Since I'm Heterozygous for A1298C , why I should avoid methylcobalamin ?
Thanks
Daniele