I finally figured out a stupidly simple (and extremely slow) way to compare all of the 23andMe data we have for 12 ME patients to 12 controls using Excel. I then calculated how big the differences are for each SNP, and ranked the SNPs starting with the biggest difference between ME patients and the controls.
In the process I did the same for Mitochondrial DNA, which is passed directly from mother to child over the generations. In the MT-DNA, we had an allele (A) for one SNP ( rs3928306 ) which was present in 7 ME patients (58.3%) and 0 controls (0%). It's a known marker for the H1 maternal haplogroup, though also appears in the J1 haplogroup, and probably some others as well. The A allele has 16.5% prevalence in the general population.
So I'm curious to know what people's haplogroups are, and which allele they have for rs3928306. There's a similar haplotype poll in this subforum, but it's far less focused. Some additional haplogroup options are included based on what's somewhat common in our results so far, and closely related haplogroups.
Please don't answer the poll yet unless you know either your maternal haplogroup or your rs3928306 status. This poll is also intended for ME/CFS patients only, with CCC- or ICC-defined ME and Post-Exertional Malaise.
In the process I did the same for Mitochondrial DNA, which is passed directly from mother to child over the generations. In the MT-DNA, we had an allele (A) for one SNP ( rs3928306 ) which was present in 7 ME patients (58.3%) and 0 controls (0%). It's a known marker for the H1 maternal haplogroup, though also appears in the J1 haplogroup, and probably some others as well. The A allele has 16.5% prevalence in the general population.
So I'm curious to know what people's haplogroups are, and which allele they have for rs3928306. There's a similar haplotype poll in this subforum, but it's far less focused. Some additional haplogroup options are included based on what's somewhat common in our results so far, and closely related haplogroups.
Please don't answer the poll yet unless you know either your maternal haplogroup or your rs3928306 status. This poll is also intended for ME/CFS patients only, with CCC- or ICC-defined ME and Post-Exertional Malaise.
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