Hello fellow members,
As some of you might recall, in my search for health I have mostly followed the enterovirus theory of ME/CFS with partial response to treatment (improving from severe-housebound to moderate-50%reduction of activities), with setbacks.
My complete history here and here#8.
I received yesterday my lab test results from Great Plains (functional/biological), which I want to share here for feedback.
What I preliminary see from the results is Toxicity (Arsenic&Mercury) (teeth ammalgams and smog are my suspects), very low potasium in hair, microbial overgrowth, high oxalic, nutritional deficiencies, major GI inflammation suggesting IBD, increase sIgA, mild dysbiosis.
I am planning what to do with these results. And whether there is anything urgent I must address. Are these results consistent with the enterovirus theory or do they suggest a co-moridity or misdiagnosis?
I'll be in LA, California for the following 4 weeks. I have an appointment with the ME/CFS guru of the enterovirus theory. Beyond the tests he ordered, I was planning to profit this trip to do the 23andME, the Nutreval GDx, and a test for pyroluria.
Is there anything additional you suggest me to do while in California for improving my chances on the basis of my story and medical record (e.g. other tests, seeing a good integrative doctor, -I even thought another ME/CFS expert who does more testing in parallel but think this is beyond my budget this time).
I'll report thereafter.
Many thanks in advance!
Sinclair
GREAT PLAINS LABS RESULTS (EXTRACT):
(I) TOXIC & ESSENTIAL ELEMENTS;
(HAIR)
TOXIC METALS:
Arsenic High: 0.11 range: < 0.08
Mercury High: 2.8 range: < 0.8
Total Toxic Representation: High
ESSENTIAL AND OTHER ELEMENTS:
Calcium High: 775 range:200-750
Potassium Low: < 3 range: 9-80
Copper High: 33 range: 11-30
Zinc High: 220 range: 130-200
Chromium Low: 0.32 range: 0.40-0.70
Selenium High: 1.2 range: 0.70-1.2
Germanium Low:0.026 range: 0.03-0.04
RATIOS:
Ca/Mg 20.4 range:4-30
Ca/P 4.73 range:0.8-8
Na/K 10.7 range: 0.5-10
Zn/Cu 6.67 range: 4-20
Zn/Cd >999 range:>800
(II) ORGANIC ACIDS TEST
Nutritional and Metabolic Profile (URINE)
INTESTINAL MICROBIAL OVERGROWTH:
(1)HIGH YEAST/FUNGAL METABOLITES:
Arabinose High 31 range ≤ 20
(2)HIGH MALABSORPTION AND BACTERIAL MARKERS:
Hippuric Acid High 981 range ≤ 241
Succinic Acid High 8.7 range ≤ 5.3
HIGH OXALATE METABOLITES:
Oxalic High 84 range: 8.9-67
HIGH KREBS CYCLE METABOLITES:
Succinic Acid High 8.7 range ≤ 5.3
NEUROTRANSMITTER METABOLITES:
HVA/VMA Ratio High 1.8 range0.32-1.4
VMA (Vanillylmandelic (noreponephrine, epinephrine) is below the mean; the HVA (Homovanillic (dopamine) is normal)
5-Hydroxyindoleacetic acid (serotonin) is below the mean
NUTRITIONAL MARKERS:
Pyridoxic acid (B6) below the mean
Pantothenic acid (B5) below the mean
Glutaric (B2 Riboflavin Marker) is normal high: suggesting deficiency
Vit C low: 0 range 10-200
CoQ10 below the mean
NAC below the mean
DETOXIFICATION:
Pyroglutamic (Glutathione marker) is normal high: suggesting deficiency
BONE METABOLITES
Low phosphoric: 770 range: 1000-4900
LOW VALUES FOR AMINO ACID METABOLITES:
(indicates absence of genetic disorders of amino acid metabolism)
but: Phenylpyruvic low:0 range 0.02-1.4
OTHER RESULTS WITH NO KNOWN CLINICAL SIGNIFICANCE ACCORDING TO LAB:
Low citramalic, 2-hydroxyphenylacetic, 4-hydroxyphenylacetic, 4-hydroxybenzoic, 4-hydroxyhippuric, 3-
indoleacetic, glyceric, glycolic, oxalic, lactic, pyruvic, 2-hydroxybutyric, fumaric, malic, aconitic, quinolinic,
kynurenic, quinolinic/5-HIAA ratio, thymine, ethylmalonic, methylsuccinic, adipic, suberic, glutaric, 3-hydroxy-3-
methylglutaric, methylcitric, or orotic
(III) COMPREHENSIVE STOOL ANALYSIS / PARASITOLOGY x 2
(STOOL)
INFLAMMATION
Lysozime High: 2100 range: <600
Lactoferrin High: 11.5 range: <7.3
White blood cells: none
Mucus: negative
IMMUNOLOGY
Secretory IgA High: 579 range: 51-204
GUT FLORA
No indicator of commensal flora
No indicator of dysbiotic flora
But, levels of some benefical bacteria are below expected: (in a 0-4 scale healthy levels are 3+ or 4+):
-Bifidobacterium spp. 1+
-Escherichia coli 2+
-Enterococcus spp. 2+
-Lactobacillus spp: No Growth
healthy levels for:
-Bacteroides fragilis group 3+
-Clostridium spp. 3+
GUT YEAST
No yeast isolated in normal flora
PARASiTHOLOGY
None Ova or Parasites
GIARDIA & CRYPTOSPORIDIUM
Negative for both Giardia intestinalis (lamblia) and Cryptosporidium
DIGESTION/ABSORPTION
All Normal (Elastase, Fat Sudan IV, Muscular fiber, Vegetal fiber, Carbs)
SHORT CHAIN FATTY ACIDS
All Normal (%Acetate, Propionate, Butirate, Valerate)
INTESTINAL HEALTH
Red Blood Cells: none
pH: 6.2 range: 6-7.8
Hidden Blood: negative
COLOR & FORM
Red/Orange
Soft
(IV) Comprehensive IgG Food Allergy Test + C. albicans, S. cerevisiae (94) – (SERUM)
Reactivity Summary
No Food Allergies in the high range
Moderate
Candida Albicans
Low
Egg Yolk, Pineapple, Mushroom, Lemon, Grapefruit, Buckwheat,
Banana, Pear, Cane, Sugar,
Apple, Tomato, Green Bean,
Garbanzo Bean, Yeast Brewers *, Grape,
Orange, Papaya, Honey,
Flax, Garlic, Egg White,
Apricot, Turkey, Wheat, Gluten,
Soybean, Pumpkin, Wheat,
Yeast Bakers *, Spinach, Yogurt,
Cod Fish, Radish, Pinto Bean,
Watermelon, Oat, Green Pepper,
Asparagus, Coconut, Carrot,
Peach, Sweet Potato, Lettuce,
Cabbage, Pecan, Rye,
Whey, Onion, Sardine,
* Saccharomyces cerevisiae
(V) GLUTEN/CASEIN PEPTIDES TEST
Both Peptides Results are normal (Casomorphin –Milk and Gliadorphin – wheat)
As some of you might recall, in my search for health I have mostly followed the enterovirus theory of ME/CFS with partial response to treatment (improving from severe-housebound to moderate-50%reduction of activities), with setbacks.
My complete history here and here#8.
I received yesterday my lab test results from Great Plains (functional/biological), which I want to share here for feedback.
What I preliminary see from the results is Toxicity (Arsenic&Mercury) (teeth ammalgams and smog are my suspects), very low potasium in hair, microbial overgrowth, high oxalic, nutritional deficiencies, major GI inflammation suggesting IBD, increase sIgA, mild dysbiosis.
I am planning what to do with these results. And whether there is anything urgent I must address. Are these results consistent with the enterovirus theory or do they suggest a co-moridity or misdiagnosis?
I'll be in LA, California for the following 4 weeks. I have an appointment with the ME/CFS guru of the enterovirus theory. Beyond the tests he ordered, I was planning to profit this trip to do the 23andME, the Nutreval GDx, and a test for pyroluria.
Is there anything additional you suggest me to do while in California for improving my chances on the basis of my story and medical record (e.g. other tests, seeing a good integrative doctor, -I even thought another ME/CFS expert who does more testing in parallel but think this is beyond my budget this time).
I'll report thereafter.
Many thanks in advance!
Sinclair
GREAT PLAINS LABS RESULTS (EXTRACT):
(I) TOXIC & ESSENTIAL ELEMENTS;
(HAIR)
TOXIC METALS:
Arsenic High: 0.11 range: < 0.08
Mercury High: 2.8 range: < 0.8
Total Toxic Representation: High
ESSENTIAL AND OTHER ELEMENTS:
Calcium High: 775 range:200-750
Potassium Low: < 3 range: 9-80
Copper High: 33 range: 11-30
Zinc High: 220 range: 130-200
Chromium Low: 0.32 range: 0.40-0.70
Selenium High: 1.2 range: 0.70-1.2
Germanium Low:0.026 range: 0.03-0.04
RATIOS:
Ca/Mg 20.4 range:4-30
Ca/P 4.73 range:0.8-8
Na/K 10.7 range: 0.5-10
Zn/Cu 6.67 range: 4-20
Zn/Cd >999 range:>800
(II) ORGANIC ACIDS TEST
Nutritional and Metabolic Profile (URINE)
INTESTINAL MICROBIAL OVERGROWTH:
(1)HIGH YEAST/FUNGAL METABOLITES:
Arabinose High 31 range ≤ 20
(2)HIGH MALABSORPTION AND BACTERIAL MARKERS:
Hippuric Acid High 981 range ≤ 241
Succinic Acid High 8.7 range ≤ 5.3
HIGH OXALATE METABOLITES:
Oxalic High 84 range: 8.9-67
HIGH KREBS CYCLE METABOLITES:
Succinic Acid High 8.7 range ≤ 5.3
NEUROTRANSMITTER METABOLITES:
HVA/VMA Ratio High 1.8 range0.32-1.4
VMA (Vanillylmandelic (noreponephrine, epinephrine) is below the mean; the HVA (Homovanillic (dopamine) is normal)
5-Hydroxyindoleacetic acid (serotonin) is below the mean
NUTRITIONAL MARKERS:
Pyridoxic acid (B6) below the mean
Pantothenic acid (B5) below the mean
Glutaric (B2 Riboflavin Marker) is normal high: suggesting deficiency
Vit C low: 0 range 10-200
CoQ10 below the mean
NAC below the mean
DETOXIFICATION:
Pyroglutamic (Glutathione marker) is normal high: suggesting deficiency
BONE METABOLITES
Low phosphoric: 770 range: 1000-4900
LOW VALUES FOR AMINO ACID METABOLITES:
(indicates absence of genetic disorders of amino acid metabolism)
but: Phenylpyruvic low:0 range 0.02-1.4
OTHER RESULTS WITH NO KNOWN CLINICAL SIGNIFICANCE ACCORDING TO LAB:
Low citramalic, 2-hydroxyphenylacetic, 4-hydroxyphenylacetic, 4-hydroxybenzoic, 4-hydroxyhippuric, 3-
indoleacetic, glyceric, glycolic, oxalic, lactic, pyruvic, 2-hydroxybutyric, fumaric, malic, aconitic, quinolinic,
kynurenic, quinolinic/5-HIAA ratio, thymine, ethylmalonic, methylsuccinic, adipic, suberic, glutaric, 3-hydroxy-3-
methylglutaric, methylcitric, or orotic
(III) COMPREHENSIVE STOOL ANALYSIS / PARASITOLOGY x 2
(STOOL)
INFLAMMATION
Lysozime High: 2100 range: <600
Lactoferrin High: 11.5 range: <7.3
White blood cells: none
Mucus: negative
IMMUNOLOGY
Secretory IgA High: 579 range: 51-204
GUT FLORA
No indicator of commensal flora
No indicator of dysbiotic flora
But, levels of some benefical bacteria are below expected: (in a 0-4 scale healthy levels are 3+ or 4+):
-Bifidobacterium spp. 1+
-Escherichia coli 2+
-Enterococcus spp. 2+
-Lactobacillus spp: No Growth
healthy levels for:
-Bacteroides fragilis group 3+
-Clostridium spp. 3+
GUT YEAST
No yeast isolated in normal flora
PARASiTHOLOGY
None Ova or Parasites
GIARDIA & CRYPTOSPORIDIUM
Negative for both Giardia intestinalis (lamblia) and Cryptosporidium
DIGESTION/ABSORPTION
All Normal (Elastase, Fat Sudan IV, Muscular fiber, Vegetal fiber, Carbs)
SHORT CHAIN FATTY ACIDS
All Normal (%Acetate, Propionate, Butirate, Valerate)
INTESTINAL HEALTH
Red Blood Cells: none
pH: 6.2 range: 6-7.8
Hidden Blood: negative
COLOR & FORM
Red/Orange
Soft
(IV) Comprehensive IgG Food Allergy Test + C. albicans, S. cerevisiae (94) – (SERUM)
Reactivity Summary
No Food Allergies in the high range
Moderate
Candida Albicans
Low
Egg Yolk, Pineapple, Mushroom, Lemon, Grapefruit, Buckwheat,
Banana, Pear, Cane, Sugar,
Apple, Tomato, Green Bean,
Garbanzo Bean, Yeast Brewers *, Grape,
Orange, Papaya, Honey,
Flax, Garlic, Egg White,
Apricot, Turkey, Wheat, Gluten,
Soybean, Pumpkin, Wheat,
Yeast Bakers *, Spinach, Yogurt,
Cod Fish, Radish, Pinto Bean,
Watermelon, Oat, Green Pepper,
Asparagus, Coconut, Carrot,
Peach, Sweet Potato, Lettuce,
Cabbage, Pecan, Rye,
Whey, Onion, Sardine,
* Saccharomyces cerevisiae
(V) GLUTEN/CASEIN PEPTIDES TEST
Both Peptides Results are normal (Casomorphin –Milk and Gliadorphin – wheat)
