The beneficial effect of FMT on non-GI disorders was a serendipitous observation. In one patient with ulcerative colitis and idiopathic thrombocytopenic purpura (ITP), FMT not only resulted in remission of ulcerative colitis but also reversal of ITP with platelet counts that increased from a mean of 97 to 195 × 109 μl.[54] Normal defecation was achieved in three patients with multiple sclerosis, who underwent FMT for chronic constipation and who also noted improvement of motor symptoms and urinary function, resulting in a regained ability to walk and removal of indwelling catheters.[55] One report described the co-development of myoclonus dystonia and chronic diarrhea in a 6-year old child who had ongoing myoclonus dystonia symptoms for 22 years.[56] FMT resulted in 90% improvement of her myoclonus dystonia symptoms, allowing her to resume employment and execute fine motor tasks, such as drinking from a cup, fastening buttons, and dressing.[56] Neurologic improvement has also been reported in one patient with Parkinson's disease after FMT for chronic constipation.[10]
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