I'm taking about 7000 mcg methyl B-12, but only a small amount of folate (~50 mcg). Some think this may cause problems for me, but I suppose the only way I could know if that were true would be to experiment, which I don't have the luxury to do at this point. I can't cut the B-12 dosage, since I need it (have a B-12 deficiency and my arms start going numb when I raise them at lower dosages), and I don't want to start on hundreds of mcg of folate -- which I accidentally did at the start of this trial and was rendered totally non-functional for a weekend on one 400 mcg dose.
In any case, I was labeled a "sensitive" even before trying methylfolate at all, so difficulty with taking almost anything is sort of what I'm used to. I get the side effects from antibiotics that only 5% get, for example.
I'd be interested to hear a theory on why a higher dose of B-12 could lead to problems with starting off on a low dose of methylfolate, though, if you have one.
Interestingly I got the dry eyes most intensely with folinic, but not methylfolate, in which I just get them slightly from time to time. The dosages were about the same.