I am doing Fredd's protocol. I was the type of responder that felt good initially then started to feel worse. I dialled back the amounts and felt not so bad, but naturally I want to increase them over time to make the protocol worthwhile. I had a little break recently from the supps, and had to admit I felt better for it. I decided to play around a little now and just take methyl folate. With the day, I had sore muscles, sore eyes, teeth felt a little sore, felt a little more lacklustre and got myself a big headache on 2 lots of400mcg. I also took some potassium in the afternoon. Similar sort of reaction I had in the past when I first jumped on methyl folate and took 400-800mg.
Okay so here is my question. the drug/medicated food supplement Deplin which is prescribed to many people with depression or mental health issues is basically methylfolate. It contains 7500mcg. Reading numerous threads on users experiences with this supplement, I don't see much in the way of negative symptoms experienced by the users, and these people are taking significantly greater amount then many of the people on this forum. What I usually read is that for some Deplin makes no difference and for many its makes a huge difference for the better to their mental well being. Quite a few of these people had genetic testing done which supported they had the MTHFR polymorphism and why they felt so much better on it. I don't understand how this supplement which is a very high dose of 5-mthf (and expensive) can result in so many clear cut outcomes within a very short period of time too for these mental health issue people, yet for lots of folks here its a drama to take.....on a fraction of the dose!
Why isn't Deplin resulting in all the nasty symptoms people incur here when they kick start the methylation cycle? (some do get symptoms which I recognize as low potassium though)
Okay so here is my question. the drug/medicated food supplement Deplin which is prescribed to many people with depression or mental health issues is basically methylfolate. It contains 7500mcg. Reading numerous threads on users experiences with this supplement, I don't see much in the way of negative symptoms experienced by the users, and these people are taking significantly greater amount then many of the people on this forum. What I usually read is that for some Deplin makes no difference and for many its makes a huge difference for the better to their mental well being. Quite a few of these people had genetic testing done which supported they had the MTHFR polymorphism and why they felt so much better on it. I don't understand how this supplement which is a very high dose of 5-mthf (and expensive) can result in so many clear cut outcomes within a very short period of time too for these mental health issue people, yet for lots of folks here its a drama to take.....on a fraction of the dose!
Why isn't Deplin resulting in all the nasty symptoms people incur here when they kick start the methylation cycle? (some do get symptoms which I recognize as low potassium though)