HB12 can help or hurt? I am confused.
Hi Kelly,
HB12 can help or hurt? I am confused
You and the whole world. In 1948 they discovered B12 and misidentified it as CyCbl because of a lab mistake. In 1959 the real AdoCbl and MeCbl were positively identified as the real b12s actually used in the human body. Almost all the research continued on CyCbl. In 1971 a famous letter was written to the Lancet (British Journal) telling some dangers of CyCbl and that the UK would be better off switching to HyCbl. About the same time France and Japan start having a tiny amount of research on MeCbl. In 1998 MeCbl became available commercially and AdoCbl shortly thereafter. Then Metafolin came along.
So if you want to know how much of other vitamins to take, the answers is based on CyCbl, HyCbl and folic acid. What do tests mean? Well, when the norming population is fed foods with folic acid and CyCbl and vitamins containing the same, whatever conditions that are created by those inactive vitamers have become normal.
The problem with CyCbl and HyCbl is that if one collects all the b12 deficiency symptoms from different countries that use different "official b12", and all the symptoms MeCbl and AdoCbl obviously heal one comes up with a list 300 or 400 symptoms long with all the physical symptoms and a whole lot of neurological symptoms that are almost entirely missing from the CyCbl/HyCbl symptoms list. Further even on the things like enlarged red cells (High MCV) don't respond well to CyCbl/HyCbl. HyCbl has a very limited range of action compared to MeCbl/AdoCbl. It helps perhaps 10% of the symptoms several percent as well. People with pernicious anemia are the living dead. The HyCbl keep them from dying but it sure doesn't restore them to health. One HyCbl injection each 3 months or 1 CyCbl injection each month is about the worst possible B12 therapy that works at all. It is based on keeping the serum cobalamin level no lower than 300pg/ml.
The majority of people in the USA have as much CyCbl and folic acid in their food supply as their bodies can use. These people are sicker than ever. They are the explosion of neurological disease including FMS/CFS/ME that we see going on right now. If these things even prevented these diseases we wouldn't be seeing them. They certainly don't cure them.
The danger of HyCbl is that while some symptoms of b12 deficiency will improve, others will worsen. The system most afflicted is the CNS. So "... if I only had a (working) brain" becomes our working theme song. The longer HyCbl is taken the larger the reaction when taking MeCbl. HyCbl never does build up active b12s to the point of generalized healing and instead worsen most of the symptoms over time while improving a few.