Just as an additional thought , some depression esp in the elderly may be due to e.g. b12 or folate probs. Alongside b1 and b3 these are recognised probs in some CFS/ME diagnosees, as you probably know. A deficiency of any or more might cause both an affective disorder and a mitochondrial dysfunction, which places any over strict depression/organic fatigue dichotomy under scrutiny.at least. while on no way compromising ideas of organic fatigue.
A google on depression and mitochondria will give loads of results, again questioning strict dichotomies of depression vs. fatigue. But that does not mean that organic fatigue is actually depression, it may mean, the reverse - that much depression has at least elements of organic fatigue and mitochondrial failure, which may make for far more effective treatments..
Ironic of course that the above organic work is being done in those with mainly mental symptoms, while CFS/ME peoplel who are marked by much physical fatigue and other physical symptoms are being treated with CBT and momolithic GET Just ridiculously ironic.
Interesting to test mito function in depressives after exercise and compare with CFS/ME diagnosees, of course.
A google on depression and mitochondria will give loads of results, again questioning strict dichotomies of depression vs. fatigue. But that does not mean that organic fatigue is actually depression, it may mean, the reverse - that much depression has at least elements of organic fatigue and mitochondrial failure, which may make for far more effective treatments..
Ironic of course that the above organic work is being done in those with mainly mental symptoms, while CFS/ME peoplel who are marked by much physical fatigue and other physical symptoms are being treated with CBT and momolithic GET Just ridiculously ironic.
Interesting to test mito function in depressives after exercise and compare with CFS/ME diagnosees, of course.