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Methylfolate dosage?

Bdeep86

Senior Member
Messages
278
Was wonder what dose of methylfolate do people generally settle on? For either Rich or Freddd? I have a lot of Bh4 issues as well so i'm wondering if I need higher doses.
 

Star-Anise

Senior Member
Messages
218
Bdeep86
Yep, I have been using the 1500mcg daily of methylB12 that I split into 3 doses - no other forms of B12 right now. I have been slowly tapering this dose up over past 3 mos, along with my methylfolate which I am at 250mcg per day right now.
I have noticed vast improvements in my energy, stamina, and cognition over past 3 months from introducing methylfolate & methylB12. As I read might be the case though I was unable to increase my doses dramatically until I got my mercury filling removed, which appeared to be leaking (yuck). I am now facing the challenge of chelation in my future...
 

helen1

Senior Member
Messages
1,033
Location
Canada
I'm on 700 mcg slowly ramped up from 100 mcg. I might be seeing an improvement, not sure.
 

Critterina

Senior Member
Messages
1,238
Location
Arizona, USA
I see people on these forums who max out at a few hundred micrograms, others who take 10-30 milligrams. It really depends on how you respond.

I am trying to substitute some folinic acid for the MTHF, since I don't have the MTHFR C677T, and since MTHF is so expensive. I take 5 mg of MTHF and one or two 800 mcg of folinic. I'm also taking TMG because of BHMT 08 mutation, so I figure I've got enough methyl groups hanging around to methylate the folinic acid. I have always had perfect skin even as a teenager and now I'm post menopausal, but my face and scalp broke out for several months when I was on 1 mg of MTHF. It's better but not great now, which is why I'm trying two of the folinic this week.