Bluebell
You might be right about VDR Bsm TT being the risk version. One study explicitly says that the T version is down-regulated. There's also a study showing less cancer risk for that (most studies show slower VDR = increased cancer risk), but the T version is also showing more risk of lupus and ANA.
Because it shows T is down-regulating the VDR gene, and VDR generates dopamine which uses up methyl groups, the slow T version should result in more methyl groups floating around than the faster C version.
To complicate things a bit, I've found one study saying T results in shorter height, and another showing that TT results in taller height. But the showing of downregulation and associated risk factors seems to be the most consistent thus far.
To make life simpler in general when reading the research, Bsm "B" = A/T, and Bsm "b" = G/C.
I haven't looked at the Taq info in detail again yet. It'll probably completely contradict all the Bsm research, knowing my luck
You might be right about VDR Bsm TT being the risk version. One study explicitly says that the T version is down-regulated. There's also a study showing less cancer risk for that (most studies show slower VDR = increased cancer risk), but the T version is also showing more risk of lupus and ANA.
Because it shows T is down-regulating the VDR gene, and VDR generates dopamine which uses up methyl groups, the slow T version should result in more methyl groups floating around than the faster C version.
To complicate things a bit, I've found one study saying T results in shorter height, and another showing that TT results in taller height. But the showing of downregulation and associated risk factors seems to be the most consistent thus far.
To make life simpler in general when reading the research, Bsm "B" = A/T, and Bsm "b" = G/C.
I haven't looked at the Taq info in detail again yet. It'll probably completely contradict all the Bsm research, knowing my luck