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I am measuring it by tissue (hair) mineral testing.@litlebluestem: how r u measuring it? Blood? Urine?
I wonder then if Mo and Mn are being depleted by the trans-sulfuration metabolites. Hmmm.
Scientists have confirmed that the pathogen that causes Lyme Disease—unlike any other known organism—can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron.
Read more at: http://phys.org/news/2013-03-scientists-reveal-quirky-feature-lyme.html#jCp
So do we not take manganese if we have Lyme? Some people say not to take magnesium because it could feed the biofilm. I don't necessarily agree with this, but it does raise some questions. Rich said that the Lyme bacteria also feed on cysteine which would then lower a person's glutathione.Hi,
Have no idea... But there is some interesting news on manganese recently...
Lyme bacteria uses manganese for enzymes.
So do we not take manganese if we have Lyme? Some people say not to take magnesium because it could feed the biofilm. I don't necessarily agree with this, but it does raise some questions. Rich said that the Lyme bacteria also feed on cysteine which would then lower a person's glutathione.
I agree. I don't know if this biofilm thing will pan out or not, but I also am more concerned about being mineral deficient. I decided to start taking lactoferrin again to bind to the iron which feeds other pathogens (if not Lyme). Lactoferrin is supposed to inhibit the biofilm, but I'm not sure I'd buy a supplement strictly for biofilm at this point. If a supplement has other benefits besides breaking up the biofilm such as Candex which also helps with candida or serrapeptase for inflammation then maybe I'd consider it.Hi,
I don't worry about feeding biofilms. I'm more concerned about becoming deficient in minerals due to poor absorbtion and gut dyfunction. Maybe the cells are incapable of distributing minerals efficiently through the system due to poor methylation?
I tried to treat biofilms one time with a EDTA chelator that pulled calcium from my GI system(I'm guessing). Either that, or the chelator didn't hold the metals well.
It caused me to crash from almost a complete remission. It took about two or three years to figure out I had to supplement with special liquid calcium. Double edged sword, because calicium inrritates the stomach, but I know I'm deficient because of bloodwork last year.
I avoid caffine to reduce biofilms. I think the caffine causes plaque on my teeth(biofilm), and maybe this is a response to excitotoxity. Maybe this is to protect from oxidation and these crazy free radicals?
Whatever the case, I doubt I can methylate while drinking caffine. I takes months to notice the benefit of caffine removal though.
I supplement manganese because when I take it, I notice an hour or two later that my GI tract responds in what I consider a favorable way. Taking it for now, at some point I need to figure out how to retest these levels including lithium.
I do take a little molybdenum also.
If you take lactoferrin for your gut, won't you still need to take some other form of iron for the blood and liver? Then won't the gut pathogens use the iron you take for the blood and liver?Lactoferrin is also good because it simply sequesters the iron for your OWN use as opposed to other gut pathogens. It won't do anything for securing iron reserves in the blood or liver, ONLY in the gut.
Acta Obstet Gynecol Scand.2009;88(9):1031-5. doi: 10.1080/00016340903117994.
Efficacy and tolerability of oral bovine lactoferrin compared to ferrous sulfate in pregnant women with iron deficiency anemia: a prospective controlled randomized study.
Nappi C, Tommaselli GA, Morra I, Massaro M, Formisano C, Di Carlo C.
Source
Department of Gynecology and Obstetrics, University of Naples Federico II, Via S. Pansini 5, Naples, Italy. nappi@unina.it
Abstract
OBJECTIVE:To compare the effects of bovine lactoferrin with ferrous sulfate on iron nutritional status and to evaluate their tolerability in 100 pregnant women with iron deficiency anemia.
DESIGN:Prospective, randomized, controlled, double blind trial.
SETTING:Obstetrics clinic of a University Department of Obstetrics and Gynecology.
POPULATION:One-hundred pregnant, healthy women to be treated either with one capsule of 100 mg bovine lactoferrin twice a day (Group A; n=49) and 520 mg ferrous sulfate once a day (Group B; n=48).
METHODS:After 30 days, we evaluated hemoglobin (Hb), serum ferritin, serum iron and total iron- binding capacity (TIBC) values. All women were asked to keep a diary of five potential gastrointestinal side effects (abdominal pain, nausea, vomiting, diarrhea and constipation). For each symptom, patients had to rate its severity according to a scale ranging from 0 (absent) to 3 (severe).
MAIN OUTCOME MEASURES:Hb level before and after treatment. Secondary outcomes were serum ferritin, serum iron and TIBC levels and the difference in symptom scores between groups.
RESULTS:In Groups A and B, Hb, serum ferritin and iron were significantly increased while TIBC was significantly reduced in comparison with basal values. No significant differences were observed between Groups A and B. The median scores of abdominal pain and constipation were significantly higher in patients treated with ferrous sulfate in comparison with those treated with bovine lactoferrin.
CONCLUSIONS:The results show that bovine lactoferrin has the same efficacy as ferrous sulfate in restoring iron deposits with significantly fewer gastrointestinal side effects.
PMID:19639462