greenshots
Senior Member
- Messages
- 399
- Location
- California
I have been slowly working through my two known defects, the CBS & the MTHFR A1298C, and have come across some controversy with the CBS C699T enzyme, at least with how Amy Yasko has explained it. I came across an old post from someone on a similar site criticizing the "lack of science" about Dr. Yasko's take on the CBS as he insisted that no one else believes that this is how the CBS enzyme works.
When I was working on recovering my daughter, I had researched methylation quite a bit & read some of the work done by Dr. James, etc. Though I haven't been able to review this recently, I did make notes and while she doesn't comment on CBS activity directly, Dr. James does mention that some of the findings in her study were unexpected. Even though this doesn't prove Dr. Yasko's theories, they were definitely in keeping with what Yasko believed to be true about the MTHFR (that it required the active version of folate as 5 MTHF, not more folate and folinic) and that CBS defects lead to less glutathione rather than more, and that more toxic wastes build up with these faster glitches. But I think whether or not these CBS defects lead to toxic overload or make more or less glutathione is most interesting and important. Then there's the matter of more sulfur and whether taking in more is good or bad since Dr. Cutler's work seems centered on this. But why all the almost angry disagreement?
Since this issue is so important in treatment, I really would like to understand it. I asked my daughter's practitioner almost 2 years ago and it seemed to me that she gave me a few fairly simple opinions but I should have written them down because I can't remember so many things nowadays. I know nothing is super easy or cut & dry like we hope but a basic understanding would help me decide on some things.
I appreciate your time,
Angela
When I was working on recovering my daughter, I had researched methylation quite a bit & read some of the work done by Dr. James, etc. Though I haven't been able to review this recently, I did make notes and while she doesn't comment on CBS activity directly, Dr. James does mention that some of the findings in her study were unexpected. Even though this doesn't prove Dr. Yasko's theories, they were definitely in keeping with what Yasko believed to be true about the MTHFR (that it required the active version of folate as 5 MTHF, not more folate and folinic) and that CBS defects lead to less glutathione rather than more, and that more toxic wastes build up with these faster glitches. But I think whether or not these CBS defects lead to toxic overload or make more or less glutathione is most interesting and important. Then there's the matter of more sulfur and whether taking in more is good or bad since Dr. Cutler's work seems centered on this. But why all the almost angry disagreement?
Since this issue is so important in treatment, I really would like to understand it. I asked my daughter's practitioner almost 2 years ago and it seemed to me that she gave me a few fairly simple opinions but I should have written them down because I can't remember so many things nowadays. I know nothing is super easy or cut & dry like we hope but a basic understanding would help me decide on some things.
I appreciate your time,
Angela