Just when I thought that leaky gut was a symptom usually exhibited in hard-to-diagnose illnesses like ME/CFS, mainstream medicine admits it is actually quite common. Intensive exercising, in this case cycling, causes a small degree of intestinal leakage in healthy people. This is explained by the fact that blood is withdrawn from the intestinal wall, weakening its structural integrity.
http://www.ncbi.nlm.nih.gov/pubmed/21811592
So why do doctors keep telling us there is no such thing as "leaky gut"? Or it's a made-up diagnosis by alternative medicine practioners? People with ME/CFS have lower blood volume and in many cases weaker connective tissues. So of course leaky gut is going to be more of an issue for us. Probably explains IBS, digestive issues, low-level toxicity of the blood stream. Not to mention, eventual adrenal stress, fatigue, PEM.
Not only that but the New York Times reported that Ibuprofen made the leaky gut even worse. If you are a patient, and you have leaky gut, then taking Ibuprofen will turn your intestine into swiss cheese (an exaggeration). http://well.blogs.nytimes.com/2012/12/05/for-athletes-risks-from-ibuprofen-use/
http://www.ncbi.nlm.nih.gov/pubmed/21811592
So why do doctors keep telling us there is no such thing as "leaky gut"? Or it's a made-up diagnosis by alternative medicine practioners? People with ME/CFS have lower blood volume and in many cases weaker connective tissues. So of course leaky gut is going to be more of an issue for us. Probably explains IBS, digestive issues, low-level toxicity of the blood stream. Not to mention, eventual adrenal stress, fatigue, PEM.
Not only that but the New York Times reported that Ibuprofen made the leaky gut even worse. If you are a patient, and you have leaky gut, then taking Ibuprofen will turn your intestine into swiss cheese (an exaggeration). http://well.blogs.nytimes.com/2012/12/05/for-athletes-risks-from-ibuprofen-use/
During the remaining visits, the men briskly rode stationary bicycles for that same hour. Before one of those rides, though, they again took 400 milligrams of ibuprofen the night before and the morning of their workouts.
At the end of each rest or ride, researchers drew blood to check whether the men’s small intestines were leaking. Dr. van Wijck found that blood levels of a protein indicating intestinal leakage were, in fact, much higher when the men combined bike riding with ibuprofen than during the other experimental conditions when they rode or took ibuprofen alone. Notably, the protein levels remained elevated several hours after exercise and ibuprofen.
The health implications of this finding are not yet clear, although they are worrisome, Dr. van Wijck said. It may be that if someone uses ibuprofen before every exercise session for a year or more, she said, “intestinal integrity might be compromised.” In that case, small amounts of bacteria and digestive enzymes could leak regularly into the bloodstream.