• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

NICE rejects belimumab for lupus

Esther12

Senior Member
Messages
13,774
Isn't rituximab out of patent soon? I think this is one of the reasons why there is little funding for trials. If it's shown to be effective, then it should be available cheaply soon after.
 

Enid

Senior Member
Messages
3,309
Location
UK
Well they are into NHS spending aren't they - what more can you expect.
 

Snow Leopard

Hibernating
Messages
5,902
Location
South Australia
30,000 per QALY they say.

The following study on CBT for CFS had a QALY of 0.03, after 16 sessions. Cost per patient is about 2000 Euros, or 1600 GBP.
http://www.biomedcentral.com/1472-6963/8/175

1/0.03 x 1600 = over 50,000 GBP, which means CBT is NOT COST EFFECTIVE ACCORDING TO THE NICE GUIDELINES and the data from this paper.

If they want to reject this drug for Lupus on this basis, then they have some explaining to do...
 

Esther12

Senior Member
Messages
13,774
30,000 per QALY they say.

The following study on CBT for CFS had a QALY of 0.03, after 16 sessions. Cost per patient is about 2000 Euros, or 1600 GBP.
http://www.biomedcentral.com/1472-6963/8/175

1/0.03 x 1600 = over 50,000 GBP, which means CBT is NOT COST EFFECTIVE ACCORDING TO THE NICE GUIDELINES and the data from this paper.

If they want to reject this drug for Lupus on this basis, then they have some explaining to do...

Is the CNT QALY thought to be per year, and with lasting results?