I've posted about this before, but still haven't managed to improve this problem.
I've for many years had both elevated total bilirubin and direct (conjugated) bilurubin. This does fluctuate, but the are elevated more often than not.
From my understanding the elevated total bilirubin is indicative of Gilbert's Syndrome (which checks out according to my 23andme results interpreted using the following info (login required):
https://www.23andme.com/you/community/phenotype/thread/3176/
This leaves the elevated direct bilirubin which is in my understanding a result of conjugation happening fine, but the bilirubin isn't able to be excreted via the bile and is indicative on cholestasis.
For many years I have had very pale stools (I'm sure this is much the same for many others). I've tried many things to stimulate bile flow, including:
Phosphatidylcholine
Lecithin
Dandelion root
Artichoke
Tribulus terrestris
Bile Acids
Ox Bile
Taurine
Glycine
Choline
Coffee enema (never again!!)
The only thing in the list that worked at all was the tribulus terrestris. I initially took this 4 1/2 years ago to try and increase testosterone and discovered it worked brilliantly for bile flow. I had perfect brown formed stools for the first time in years. Unfortunately, this herb gave me extreme nervous system side effects, so couldn't continue it. I've no doubt this must have something to do with the increase in luteinizing hormone on the nervous system, I'm unable to figure out how though.
Have many other PWCs had this much trouble getting bile flow happening? Has anyone had success? If so, what with?
Has improving methylation possibly had a positive effect on bile flow?
hixxy
I've for many years had both elevated total bilirubin and direct (conjugated) bilurubin. This does fluctuate, but the are elevated more often than not.
From my understanding the elevated total bilirubin is indicative of Gilbert's Syndrome (which checks out according to my 23andme results interpreted using the following info (login required):
https://www.23andme.com/you/community/phenotype/thread/3176/
This leaves the elevated direct bilirubin which is in my understanding a result of conjugation happening fine, but the bilirubin isn't able to be excreted via the bile and is indicative on cholestasis.
For many years I have had very pale stools (I'm sure this is much the same for many others). I've tried many things to stimulate bile flow, including:
Phosphatidylcholine
Lecithin
Dandelion root
Artichoke
Tribulus terrestris
Bile Acids
Ox Bile
Taurine
Glycine
Choline
Coffee enema (never again!!)
The only thing in the list that worked at all was the tribulus terrestris. I initially took this 4 1/2 years ago to try and increase testosterone and discovered it worked brilliantly for bile flow. I had perfect brown formed stools for the first time in years. Unfortunately, this herb gave me extreme nervous system side effects, so couldn't continue it. I've no doubt this must have something to do with the increase in luteinizing hormone on the nervous system, I'm unable to figure out how though.
Have many other PWCs had this much trouble getting bile flow happening? Has anyone had success? If so, what with?
Has improving methylation possibly had a positive effect on bile flow?
hixxy