- Messages
- 12
Hi there,
I'm very glad I found this forum, as you all seem so knowledgeable. I'm 22 years old, have been struggling along with sub-par energy levels and general poor health since my teens, and have been looking for a solution ever since. I've tried things like the candida diet, detoxing, cutting out gluten, and most recently dessicated thyroid, which only made me feel 10x worse. I recently learnt about the MTHFR mutation, and without being tested (or sufficiently informed!) I plunged into a protocol which involved taking sublingual methyl-b12 and folinic acid, alongside vits A,C,D, chromium, zinc & magnesium oil. My first reaction to the methyl-b12 was anger outbursts, acne outbreaks & general emotional instability, so I cut down to taking 1000mcg every other day. A couple of weeks after that settled down, I started taking folinic acid, thinking it was as good as taking methylfolate (I now know better). After a week or 2 on the B12 + folinic, I started experiencing restless leg syndrome (something I've never had in my life, and which I now know from Freddd is linked to potassium deficiency), severe depression & suicidal thoughts, irritability, extreme fatigue, and poor skin/nail health. As I said, until finding this forum I had no idea about the danger of potassium deficiency nor the consequences of taking folic/folinic acid. My questions are......
1) does my reaction to these supplements mean that they are working for me, thus I have some kind of MTHFR mutation?
2) if so, will I have to take b12 & methylfolate all my life?
3) could someone please explain methylation/methyl donors? I am confused by the whole process really.
4) here in the UK, I can only get one brand of adenosylb12, which has added folic acid. Does the positive effect of the b12 negate the potential harm of taking folic acid? Would taking methylfolate at the same time be a wise idea, or does folic acid have an advantage when the 2 are taken simultaneously?
It may seem a bit hasty, beginning a protocol like this without knowing much about why it might work or the mechanisms behind it, but it just seemed right to try it and I didn't see any harm in doing so. I have seen some improvements as well - like better energy, feeling more sociable, just greater wellbeing all round (especially now I've started to correct the potassium deficiency). I'd appreciate it if people more experienced than I could comment and answer my questions. Thank you! :Retro smile:
I'm very glad I found this forum, as you all seem so knowledgeable. I'm 22 years old, have been struggling along with sub-par energy levels and general poor health since my teens, and have been looking for a solution ever since. I've tried things like the candida diet, detoxing, cutting out gluten, and most recently dessicated thyroid, which only made me feel 10x worse. I recently learnt about the MTHFR mutation, and without being tested (or sufficiently informed!) I plunged into a protocol which involved taking sublingual methyl-b12 and folinic acid, alongside vits A,C,D, chromium, zinc & magnesium oil. My first reaction to the methyl-b12 was anger outbursts, acne outbreaks & general emotional instability, so I cut down to taking 1000mcg every other day. A couple of weeks after that settled down, I started taking folinic acid, thinking it was as good as taking methylfolate (I now know better). After a week or 2 on the B12 + folinic, I started experiencing restless leg syndrome (something I've never had in my life, and which I now know from Freddd is linked to potassium deficiency), severe depression & suicidal thoughts, irritability, extreme fatigue, and poor skin/nail health. As I said, until finding this forum I had no idea about the danger of potassium deficiency nor the consequences of taking folic/folinic acid. My questions are......
1) does my reaction to these supplements mean that they are working for me, thus I have some kind of MTHFR mutation?
2) if so, will I have to take b12 & methylfolate all my life?
3) could someone please explain methylation/methyl donors? I am confused by the whole process really.
4) here in the UK, I can only get one brand of adenosylb12, which has added folic acid. Does the positive effect of the b12 negate the potential harm of taking folic acid? Would taking methylfolate at the same time be a wise idea, or does folic acid have an advantage when the 2 are taken simultaneously?
It may seem a bit hasty, beginning a protocol like this without knowing much about why it might work or the mechanisms behind it, but it just seemed right to try it and I didn't see any harm in doing so. I have seen some improvements as well - like better energy, feeling more sociable, just greater wellbeing all round (especially now I've started to correct the potassium deficiency). I'd appreciate it if people more experienced than I could comment and answer my questions. Thank you! :Retro smile: