does a slightly high RBC suggest I am a poor methylator

[anniekim]

A full blood count I had a while back came out normal apart from slightly high red blood count. Does anyone know whether a high RBC can suggest I am a poor methylator? Many thanks..

 

[anniekim]

Ah, think I am getting confused. I think it's a high MCV that indicates methylation problems as opposed to high rbc. So the size of the red blood cells as opposed to how many....

 

[Freddd]

Hi Annikim,

High MCV, high MCH, low platelet, lots of multisegmented neuraphils, some white cell abnormalities I forget the specifics of and other things. Low mb12 and/or methylfolate can cause these along with some other things. Every doc I saw asked if I had trouble with bleeding. They also all kept fishing for how much alchohol I was drinking. I would start to tell them "About 2 sixpacks per" interupt me and the doc would say "per day" and I would say "no, per year".

My blood profile looked like an alcoholic's with many deficiencies.

 

[anniekim]

Thanks Fredd. I take it I'm right high rbc does not suggest a methylation problem? My MCV etc are all within normal range.

 

[Freddd]

Thanks Fredd. I take it I'm right high rbc does not suggest a methylation problem? My MCV etc are all within normal range.

Hi Anniekim,

You mean "normal" from before nationwide endemic b12 and folate deficiencies or after?

the difference is >93 old, > 100 or even > 101 depending where you are.

What the the NUMBERS, "normal" is a statistical abstraction and even aberation since average of people too high results in "normal" being too high. Same wirth MCH.

 

[anniekim]

Ok, but may I still ask does high rbc suggest problems with methylation? Many thanks

 

[Freddd]

Ok, but may I still ask does high rbc suggest problems with methylation? Many thanks

I have no idea. What were the numbers for the MCV and MCH?