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I've been told a series of papers on XMRV will be released tomorrow afternoon with major implications for XMRV. I see from another thread that there is a chat being conducted by a member of the Blood Working Group. Things are apparently coming together rather rapidly. Be ready for some big news.
I've been told a series of papers on XMRV will be released tomorrow afternoon with major implications for XMRV. I see from another thread that there is a chat being conducted by a member of the Blood Working Group. Things are apparently coming together rather rapidly. Be ready for some big news.
Analysis of single nucleotide polymorphisms in XMRV patient-derived integration sites reveals contamination from cell lines acutely infected by XMRV
Alice Rusmevichientong1, Jaydip Das Gupta2, Petra S. Elias1, Robert H. Silverman2, and Samson A. Chow1,*
1 Department of Molecular and Medical Pharmacology, and UCLA AIDS Institute, UCLA School of Medicine, Los Angeles, California 90095
2 Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195
We analyzed xenotropic murine leukemia virus-related virus (XMRV) integration site sequences previously identified from human prostate tissues for single nucleotide polymorphisms (SNPs) to discriminate between patient and potential cell line sources of the proviruses. The SNPs of two integration sites were identical to those in cell lines but not the patients, whereas the data on the remaining 12 integration sites were inconclusive. Our results provide direct evidence for contamination during analysis of XMRV integration sites.
What a coincidence that all of this is now being published all at once... again. Can someone say orchestrated?