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What does the onset of ME/CFS look like with the microbiome over the first 6 days!

I just received my uBiome report for a sample taken 6 days after a sudden onset ME flare. It was sudden onset because over 15 minutes I could feel my entire body shift and booked off sick for the rest of that day (and following week). The cause was stress, the cause of 40% of ME cases according to studies (the other 60% were infections).
I have two normal health ubiome for reference (each at least 6 months apart). As you can see with this first chart, three important groups did a nose dive.

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Only Lactobacillus Helveticus (not in probiotic that I was taking)
This is repeated with other groups:

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Other items are unchanged, such as diversity
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And looking at various levels of bacteria, nothing jumps out
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Microbiome Site Analysis
I uploaded the JSON to
http://microbiomeprescription.azurewebsites.net/upload , and then look at various reports.
What shows up in the comparison is that High Counts across all conditions went up by 30%.
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Oldest on left, newest on right
Some specific jumps:
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In terms of the experimental End Produces, we also see some interesting shifts (most numbers were roughly the same)
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Large drops in following genus (was normal-range earlier and often went down to -98%)
  • Akkermansia
  • Anaerococcus
  • Dialister
  • Enterobacter
  • Porphyromonas
  • Staphylococcus
  • Succiniclasticum
Major increases in following genus:
Bottom Line
First item is that this is likely a unique report — 6 days after onset. A diagnosis of ME/CFS classically requires 6 months of extensive no-results testing, so any ubiome test result would be after a significant progression of microbiome shifts.
Lactic acid producers has crashed, histamine and hydrogen peroxide producers have increased. Significant shift towards a IBS/IBD profile.
Probiotics
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After preparing this post, I started with Enterogermina (4 Bacillus clausii in suspension) and within 12 hours found significant changes including:
  • Stopping high frequency stool movements that had been ongoing for 4 days
  • Change of mood – from borderline depression to very mellow and very very laid back.
It was interesting to note the list of avoid
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Plans going forward (reduce the high ones)
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One of the items, choline deficiency, means that I should cut out my usual 2 eggs each morning because they are high in choline.
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Some of the strong avoids were interesting (and unexpected)
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Author
Lassesen
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2 min read
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