An alternative hypothesis: Chronic activation of the innate immune system through upregulation of TNF alpha and NF-kappa expression results in sodium channelophy and an upregulation of the sensitivity of the sympathetic nervous system through increased voltage-gated sodium channel stimulation:
http://www.sciencedirect.com/science/article/pii/S0014488610004188
http://qatar-weill.cornell.edu/research/faculty/busselberg/publications/TNFalpha ion channels.pdf
http://www.sciencedirect.com/science/article/pii/S0014488610004188
http://qatar-weill.cornell.edu/research/faculty/busselberg/publications/TNFalpha ion channels.pdf