In this blog post I'm going to try to collect information on all the possible co-factors one might need or incur a deficiency when doing Freddd's version of the SMP. If you find anything that might belong here please post in the comments and I will add to the page after review.
Freddd's reply to how much MB12 to take when ramping up MFolate: click here
the beginning of the post click here (How to Titrate to Get Out of Donut Hole Insufficiency)
Freddd's list of cofactors:
(My Note: Potassium and C, I believe, should be taken apart from the other supplements as they diminish the effect of some.)
Dr. Ben:
Link to my blog post about Dr. Ben's MTHFRAde
List of Possible B-Complex formulas:
Notes on preventing methyl-folate side effects:
http://mthfr.net/preventing-methylfolate-side-effects/2014/11/26/
Notes on taking cofactors:
How much Potassium do you take?
HowIrecovered.com's Understanding Potassium
Gondwanaland: (regarding magnesium)
mgk
Victronix
minkeygirl
Mg deficiency affects MTHFR? Really?
Lithium has been discussed as something that helps get the MB12 and MFolate into the cells (expand on this)
Nancy Mullan's article on Lithium (scroll down)
"Lithium induces B12 transport into the cells thus driving the long route. This can happen with just the standing levels of B12 without additional supplementation. B12 binding capacity as well as white count will go up in the presence of lithium. B12 deficiency is known to lead to degeneration of the central nervous system and psychiatric disturbances such as affective disorders and manic psychosis. Violent criminals as a group have the lowest levels of lithium in hair. There is not only a relationship between lithium, B12 and folate, but also between low lithium and anxiety, aggression, bipolar disorder and SZ."
Lithium, B12 and mercury and sleep
aquariusgirl
arx
Vitamin D causes potassium and methylfolate deficiency.
Too Much Vitamin D, Carolyn Dean
Freddd
Vitamin D is probably the most frequent deadlock item outside of the Deadlock Quartet. I've never seen anybody with methylation startup with E, but have seen quite a few with D.
Freddd
I found that TMG brought ATP wiring down quite a bit by changing the balance. Good luck.
Freddd's reply to how much MB12 to take when ramping up MFolate: click here
the beginning of the post click here (How to Titrate to Get Out of Donut Hole Insufficiency)
Freddd's list of cofactors:
(My Note: Potassium and C, I believe, should be taken apart from the other supplements as they diminish the effect of some.)
Dr. Ben:
Link to my blog post about Dr. Ben's MTHFRAde
List of Possible B-Complex formulas:
Notes on preventing methyl-folate side effects:
http://mthfr.net/preventing-methylfolate-side-effects/2014/11/26/
Notes on taking cofactors:
How much Potassium do you take?
HowIrecovered.com's Understanding Potassium
Gondwanaland: (regarding magnesium)
mgk
Victronix
minkeygirl
Mg deficiency affects MTHFR? Really?
Lithium has been discussed as something that helps get the MB12 and MFolate into the cells (expand on this)
Nancy Mullan's article on Lithium (scroll down)
"Lithium induces B12 transport into the cells thus driving the long route. This can happen with just the standing levels of B12 without additional supplementation. B12 binding capacity as well as white count will go up in the presence of lithium. B12 deficiency is known to lead to degeneration of the central nervous system and psychiatric disturbances such as affective disorders and manic psychosis. Violent criminals as a group have the lowest levels of lithium in hair. There is not only a relationship between lithium, B12 and folate, but also between low lithium and anxiety, aggression, bipolar disorder and SZ."
Lithium, B12 and mercury and sleep
aquariusgirl
arx
Magnesium is very important for vitamin d3, it seems. I feel worse when taking high doses (>10k) of vitamin d3 but magnesium and k2 make it better. It does activate the immune system and d3's anti-inflammatory effect is very much visible on my skin the very next day! 
Keep feeding the building blocks that D3 needs and go slow, that's what I did and turned out better than only D3 for me
Keep feeding the building blocks that D3 needs and go slow, that's what I did and turned out better than only D3 for me
Too Much Vitamin D, Carolyn Dean
Freddd
Vitamin D is probably the most frequent deadlock item outside of the Deadlock Quartet. I've never seen anybody with methylation startup with E, but have seen quite a few with D.
Freddd
I found that TMG brought ATP wiring down quite a bit by changing the balance. Good luck.
Likes:
jason30
