SIBO and CFS/FM/IBS constantly shows a pattern of low or no Bifidobacterium, Lactobacillus and E.Coli. This was first reported in 1998 at a conference in Australia. With these bacteria missing — how does it impact items like amino acids etc…
This is a technical post attempting to illustrate why things go wrong when they are missing — and why their absence leads to various supplements being needed (causation!)
All data is from datapunk.net ( Peter D’Adamo, currently a Distinguished Professor of Health Sciences at the University of Bridgeport, where he direct the Center of Excellence in Generative Medicine.)
ENDPRODUCTS For Bifidobacterium Genus
This is likely far above most readers brain-fog levels, but I believe it does illustrate that it is not just some inconsequential bacteria that you are missing. These three groups impact a lot of stuff and missing end products cascade across the body’s system.
This is a technical post attempting to illustrate why things go wrong when they are missing — and why their absence leads to various supplements being needed (causation!)
All data is from datapunk.net ( Peter D’Adamo, currently a Distinguished Professor of Health Sciences at the University of Bridgeport, where he direct the Center of Excellence in Generative Medicine.)
ENDPRODUCTS For Bifidobacterium Genus
- 2-Oxocarboxylic acid metabolism
- ABC transporters
- Alanine, aspartate and glutamate metabolism
- Amino sugar and nucleotide sugar metabolism
- Aminoacyl-tRNA biosynthesis
- Arachidonic acid metabolism
- E. Coli only
- Arginine and proline metabolism
- Arginine biosynthesis
- Ascorbate and aldarate metabolism
- E. Coli only
- Bacterial chemotaxis
- E. Coli only
- Bacterial secretion system
- Base excision repair
- Benzoate degradation
- Lacto and E. Coli only
- Biosynthesis of amino acids
- Biosynthesis of antibiotics
- Biosynthesis of secondary metabolites
- Biosynthesis of siderophore group nonribosomal peptides
- E. Coli only
- Biosynthesis of unsaturated fatty acids
- Biotin metabolism
- Butanoate metabolism
- C5-Branched dibasic acid metabolism
- Bifi and E.Coli only
- Caprolactam degradation
- E. Coli only
- Carbapenem biosynthesis
- Bifi and E. Coli only
- Carbon metabolism
- Cationic antimicrobial peptide (CAMP) resistance
- Lacto only
- Chloroalkane and chloroalkene degradation
- Citrate cycle (TCA cycle)
- Cyanoamino acid metabolism
- Cysteine and methionine metabolism
- D-Alanine metabolism
- D-Glutamine and D-glutamate metabolism
- DNA replication
- Degradation of aromatic compounds
- Dioxin degradation
- E. Coli only
- Ether lipid metabolism
- E. Coli only
- Fatty acid biosynthesis
- Fatty acid degradation
- Fatty acid metabolism
- Flagellar assembly
- E. Coli only
- Fluorobenzoate degradation
- E. Coli only
- Folate biosynthesis
- Fructose and mannose metabolism
- Galactose metabolism
- Geraniol degradation
- E. Coli only
- Glutathione metabolism
- Glycerolipid metabolism
- Glycerophospholipid metabolism
- Glycine, serine and threonine metabolism
- Glycolysis / Gluconeogenesis
- Glyoxylate and dicarboxylate metabolism
- Histidine metabolism
- Homologous recombination
- Inositol phosphate metabolism
- Bifi and E. Coli only
- Insulin resistance
- Lysine biosynthesis
- Lysine degradation
- E. Coli only
- Metabolic pathways
- Methane metabolism
- Microbial metabolism in diverse environments
- Mismatch repair
- Monobactam biosynthesis
- Naphthalene degradation
- Nicotinate and nicotinamide metabolism
- Nitrogen metabolism
- Nonribosomal peptide structures
- Lacto and Bifi only
- Novobiocin biosynthesis
- Bifo only
- Nucleotide excision repair
- One carbon pool by folate
- Other glycan degradation
- Oxidative phosphorylation
- Pantothenate and CoA biosynthesis
- Pentose and glucuronate interconversions
- Pentose phosphate pathway
- Peptidoglycan biosynthesis
- Phenylalanine metabolism
- Phenylalanine, tyrosine and tryptophan biosynthesis
- Bifo only
- Phosphotransferase system (PTS)
- Polyketide sugar unit biosynthesis
- Bifo and E.Coli only
- Porphyrin and chlorophyll metabolism
- Bifo only
- Propanoate metabolism
- Protein export
- Purine metabolism
- Pyrimidine metabolism
- Pyruvate metabolism
- RNA degradation
- RNA polymerase
- Riboflavin metabolism
- Ribosome
- Secondary bile acid biosynthesis
- Bifo and Lacto only
- Selenocompound metabolism
- Sphingolipid metabolism
- Starch and sucrose metabolism
- Streptomycin biosynthesis
- Sulfur metabolism
- Sulfur relay system
- Lacto and E. Coli only
- Synthesis and degradation of ketone bodies
- Lacto only
- Taurine and hypotaurine metabolism
- Terpenoid backbone biosynthesis
- Thiamine metabolism
- Two-component system
- Tyrosine metabolism
- Ubiquinone and other terpenoid-quinone biosynthesis
- Bifo and E.Coli only
- Valine, leucine and isoleucine biosynthesis
- Valine, leucine and isoleucine degradation
- Vancomycin resistance
- Vitamin B6 metabolism
- Xylene degradation
- E. Coli only
- alpha-Linolenic acid metabolism
- E. Coli only
- beta-Alanine metabolism
- E. Coli only
- beta-Lactam resistance
This is likely far above most readers brain-fog levels, but I believe it does illustrate that it is not just some inconsequential bacteria that you are missing. These three groups impact a lot of stuff and missing end products cascade across the body’s system.
- Missing Histidine metabolism –> Histamine sensitivity?
- Missing Degradation of aromatic compounds –> MCS?
Likes:
WendyM, Chocolove and Ben H
