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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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ramakentesh

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My Alternative Hypothesis
ramakentesh
1 min read
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436
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An alternative hypothesis: Chronic activation of the innate immune system through upregulation of TNF alpha and NF-kappa expression results in sodium channelophy and an upregulation of the sensitivity of the sympathetic nervous system through increased voltage-gated sodium channel stimulation...
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my hypothesis
ramakentesh
1 min read
Views
482
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4
User Blogs
My hypothesis: CFS/ME is a manifestation of increased cerebral lactate, impaired glucose metabolism and reduced cerebral antioxidant activity as a result of postural reductions in blood flow to the brain. These reductions may manifest as POTS or NMH but may also manifest as abnormal cerebral...

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ramakentesh
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