A New Decade of ME Research: The 11th Invest in ME International ME Conference 2016
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zopiclone versus zolpidem which is better?

Discussion in 'General Treatment' started by EnduringAngel, Oct 27, 2014.

  1. EnduringAngel

    EnduringAngel

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    "Hampshire, UK"
    Anyone have any views on which is better for people with ME?

    Any experiences you would be able to share would be great. My sleep is so so bad.
     
  2. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    Alternate both with alternating other meds to avoid tolerance. But I find zopiclone keeps me asleep longer.
     
  3. Countrygirl

    Countrygirl Senior Member

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    I found that zolpidem gave an intolerable side effect: severe agitation which I have never before experienced in my life. It was truly awful and has given me a great sympathy for anyone who suffers from this horrid condition. Perhaps it was a greatly enhanced case of the 'wired' sensation that many of us experience with ME and I would say without doubt that this distressing symptom was more unpleasant than even severe ME. When I realised that this sudden onset condition corresponded with starting zolpidem, I stopped the medication and the symptom vanished.........thank goodness.

    I use zopiclone, but that has one embarrassing side effect for me: sleepwalking and binge eating in my sleep. I would find in the morning that I had eaten whole cakes including a large Christmas cake that I had made and on numerous occasions, whole large tubs of ice cream. :redface: It was a terrible waste as I had no memory of eating the scrummy food which was tragic. :cry::rofl: If I didn't live alone, I would have blamed someone else for the scenes of screwed up food wrappings that were tossed on the kitchen floor instead of being placed tidily in the bin and the missing food. It took me ten years of attempting to hide this embarrassing problem before I read that sleep walking as well as the nocturnal binge eating are two of the side effects. I have now found I can control this problem if I take no more than a half of a 7.5 mg of zopiclone which lasts me for about four hours. Unlike temazapam,it doesn't result in the poisoned feeling that one can have in the morning.

    As for choosing between zolpidem and zopiclone there is no contest for me: zopiclone everytime, but do place padlocks on your fridge, freezer and larder and give someone else the key. :):(
     
    Last edited: Oct 28, 2014
  4. Apple

    Apple Senior Member

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    I've only taken them a few times. Zopiclone got me to sleep more quickly. Zolpidem seems to have scarier side effects (such as hallucinations/memory blanks), although I've not experienced that myself.

    For longer term issues - Amitriptyline has really helped me.
     
  5. EnduringAngel

    EnduringAngel

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    Thanks for that people. So so true about the eating, not in my sleep though thank goodness, but after I've taken them I simply have to eat! gonna get huge at this rate. I was on nytol for like 10 years until I realised it was masking a possible mast cell disorder, still waiting to get diagnosed. But def need something more long term sleep wise and for pain.

    Really don't want to go on anti depressants though... any other ideas anyone? was thinking maybe muscle relaxant?
     
  6. Countrygirl

    Countrygirl Senior Member

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    Yes, baclofen. I have found this a most useful medication.
     
  7. maryb

    maryb iherb code TAK122

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    Also remember Zopiclone is very addictive, I'm now on 3/4 of a half tablet, been on iZop about 4/5yrs, but just don't seem to be able to reduce it down. I'm giving myself a break and accepting it at present as already feeling so rough with other stuff. Just wanted to reinforce that, if I had the choice again I wouldn't take it.
     
  8. Jenny

    Jenny Senior Member

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    I've taken zopiclone on an occasional basis for about 3 years. I only take half a 3.5 mg tablet on average twice a week. It gets me to sleep within half an hour or so,pretty reliably. Lack of sleep affects me really badly, so it's been a fantastic find.
     
  9. maryb

    maryb iherb code TAK122

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    @Jenny
    wish I'd taken it as you have on an occasional basis. Several people on here rotate sleep meds, so as not to become dependent, that seems to be the best idea.
    So you have the 3.5mg tablets, I have 7.5mg didn't know they did smaller ones. I keep cutting down the half more and more so hopefully I'll get there at some point. I'm going to try the l-theanine tonight, have to find something else that works as well as Zop for getting me to sleep.
     
  10. Jenny

    Jenny Senior Member

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    GP won't give me any more than 14 tabs every couple of months, so I can only take them infrequently!

    Have you tried very low dose melatonin? I take 0.3 mg occasionally, and it sometimes helps.

    Good luck!
     

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