So in discovering that Acai helps me greatly, and that it modulates nitric oxide...I did some research on nitric oxide's roll in CFS, and there is this thing called the Pall Protocol. Verrrry similar to what is talked about here by people like Rich and Freddd. Honestly, some of these supplements he singles in on, even some of the random things, have REALLY helped me. I also have MCS. I think there could be something to this, for a subset of us. Yes, you'll recognize a lot of this...TMG, Glutathione, etc etc. Below are 3 links (first link very complex, second link simpler, third is an overview of the conditions such as CFIDS on Pall's radar). I would read the third, then second, then first. Sorry, not gonna swap 'em now. The first two links tell you what supps to take if you keep scrolling through: http://chronicfatigue.about.com/gi/o.htm?zi=1/XJ&zTi=1&sdn=chronicfatigue&cdn=health&tm=322&f=00&tt=2&bt=1&bts=1&zu=http://sprident.com/martin-pall/ http://planetthrive.com/2009/06/pall-noonoo-protocol/ http://chronicfatigue.about.com/od/treatmentprotocols/a/Pall_Protocol.htm An overview, including all our favorites like orthostatic intolerance, bacteria/infections, chemical triggers, etc. -he talks about Minocycline in first link. This helped my sleep cycle instantly and remarkably. Whereas Doxycycline was a nightmare. -NAC helps me a lot -I saw the second link mentions Hydroxy B12, which helps me a lot, sometimes seemingly more than Methyl B12 -Acai is one of the N.O. helpers he has mentioned, though he talks about other berries too. I make it no mystery on Phoenix Rising that for me, Acai, freeze dried capsules by Now, have been magnificent and continue to help tons. But this is the first I've seen where a doctor is saying, "take Acai and this is why." OKAY! WILL DO! I personally don't believe we all have the same cause for our CFS, but I think that for maybe 20-30% of us, this could be the cause, or at least it's on the right track. Something is up!!!!!